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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.
Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Rådmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Förster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M. Friedmann Angeli JP, et al. Among authors: bornkamm gw. Nat Cell Biol. 2014 Dec;16(12):1180-91. doi: 10.1038/ncb3064. Epub 2014 Nov 17. Nat Cell Biol. 2014. PMID: 25402683 Free PMC article.
System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
Mandal PK, Seiler A, Perisic T, Kölle P, Banjac Canak A, Förster H, Weiss N, Kremmer E, Lieberman MW, Bannai S, Kuhlencordt P, Sato H, Bornkamm GW, Conrad M. Mandal PK, et al. Among authors: bornkamm gw. J Biol Chem. 2010 Jul 16;285(29):22244-53. doi: 10.1074/jbc.M110.121327. Epub 2010 May 12. J Biol Chem. 2010. PMID: 20463017 Free PMC article.
12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases.
Conrad M, Sandin A, Förster H, Seiler A, Frijhoff J, Dagnell M, Bornkamm GW, Rådmark O, Hooft van Huijsduijnen R, Aspenström P, Böhmer F, Ostman A. Conrad M, et al. Among authors: bornkamm gw. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15774-9. doi: 10.1073/pnas.1007909107. Epub 2010 Aug 23. Proc Natl Acad Sci U S A. 2010. PMID: 20798033 Free PMC article.
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis.
Altamura S, Vegi NM, Hoppe PS, Schroeder T, Aichler M, Walch A, Okreglicka K, Hültner L, Schneider M, Ladinig C, Kuklik-Roos C, Mysliwietz J, Janik D, Neff F, Rathkolb B, de Angelis MTH, Buske C, Silva ARD, Muedder K, Conrad M, Ganz T, Kopf M, Muckenthaler MU, Bornkamm GW. Altamura S, et al. Among authors: bornkamm gw. Haematologica. 2020 Apr;105(4):937-950. doi: 10.3324/haematol.2018.212977. Epub 2019 Jun 27. Haematologica. 2020. PMID: 31248967 Free PMC article.
240 results