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Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Nat Commun. 2019 Sep 27;10(1):4423. doi: 10.1038/s41467-019-12272-9.
Nat Commun. 2019.
PMID: 31562312
Free PMC article.
Publisher Correction: Molecular basis of microhomology-mediated end-joining by purified full-length Polθ.
Black SJ, Ozdemir AY, Kashkina E, Kent T, Rusanov T, Ristic D, Shin Y, Suma A, Hoang T, Chandramouly G, Siddique LA, Borisonnik N, Sullivan-Reed K, Mallon JS, Skorski T, Carnevale V, Murakami KS, Wyman C, Pomerantz RT.
Black SJ, et al. Among authors: borisonnik n.
Nat Commun. 2020 Apr 9;11(1):1831. doi: 10.1038/s41467-020-15551-y.
Nat Commun. 2020.
PMID: 32273507
Free PMC article.
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Polθ promotes the repair of 5'-DNA-protein crosslinks by microhomology-mediated end-joining.
Chandramouly G, Liao S, Rusanov T, Borisonnik N, Calbert ML, Kent T, Sullivan-Reed K, Vekariya U, Kashkina E, Skorski T, Yan H, Pomerantz RT.
Chandramouly G, et al. Among authors: borisonnik n.
Cell Rep. 2021 Mar 9;34(10):108820. doi: 10.1016/j.celrep.2021.108820.
Cell Rep. 2021.
PMID: 33691100
Free PMC article.
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Polθ reverse transcribes RNA and promotes RNA-templated DNA repair.
Chandramouly G, Zhao J, McDevitt S, Rusanov T, Hoang T, Borisonnik N, Treddinick T, Lopezcolorado FW, Kent T, Siddique LA, Mallon J, Huhn J, Shoda Z, Kashkina E, Brambati A, Stark JM, Chen XS, Pomerantz RT.
Chandramouly G, et al. Among authors: borisonnik n.
Sci Adv. 2021 Jun 11;7(24):eabf1771. doi: 10.1126/sciadv.abf1771. Print 2021 Jun.
Sci Adv. 2021.
PMID: 34117057
Free PMC article.
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Polλ promotes microhomology-mediated end-joining.
Chandramouly G, Jamsen J, Borisonnik N, Tyagi M, Calbert ML, Tredinnick T, Ozdemir AY, Kent T, Demidova EV, Arora S, Wilson SH, Pomerantz RT.
Chandramouly G, et al. Among authors: borisonnik n.
Nat Struct Mol Biol. 2023 Jan;30(1):107-114. doi: 10.1038/s41594-022-00895-4. Epub 2022 Dec 19.
Nat Struct Mol Biol. 2023.
PMID: 36536104
Free PMC article.
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Author Correction: Polλ promotes microhomology-mediated end-joining.
Chandramouly G, Jamsen J, Borisonnik N, Tyagi M, Calbert ML, Tredinnick T, Ozdemir AY, Kent T, Demidova EV, Arora S, Wilson SH, Pomerantz RT.
Chandramouly G, et al. Among authors: borisonnik n.
Nat Struct Mol Biol. 2023 Jul;30(7):1048. doi: 10.1038/s41594-023-00993-x.
Nat Struct Mol Biol. 2023.
PMID: 37059901
No abstract available.
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Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.
Fried W, Tyagi M, Minakhin L, Chandramouly G, Tredinnick T, Ramanjulu M, Auerbacher W, Calbert M, Rusanov T, Hoang T, Borisonnik N, Betsch R, Krais JJ, Wang Y, Vekariya UM, Gordon J, Morton G, Kent T, Skorski T, Johnson N, Childers W, Chen XS, Pomerantz RT.
Fried W, et al. Among authors: borisonnik n.
Nat Commun. 2024 Apr 5;15(1):2862. doi: 10.1038/s41467-024-46593-1.
Nat Commun. 2024.
PMID: 38580648
Free PMC article.
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