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Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants.
Hong J, Kwon HJ, Cachau R, Chen CZ, Butay KJ, Duan Z, Li D, Ren H, Liang T, Zhu J, Dandey VP, Martin NP, Esposito D, Ortega-Rodriguez U, Xu M, Borgnia MJ, Xie H, Ho M. Hong J, et al. Among authors: borgnia mj. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2201433119. doi: 10.1073/pnas.2201433119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476528 Free PMC article.
Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold.
Gordon J, Chapus FL, Viverette EG, Williams JG, Deterding LJ, Krahn JM, Borgnia MJ, Rodriguez J, Warren AJ, Stanley RE. Gordon J, et al. Among authors: borgnia mj. Nat Commun. 2022 Nov 9;13(1):6783. doi: 10.1038/s41467-022-34610-0. Nat Commun. 2022. PMID: 36351913 Free PMC article.
Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15.
Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Pillon MC, et al. Among authors: borgnia mj. bioRxiv [Preprint]. 2020 Aug 11:2020.08.11.244863. doi: 10.1101/2020.08.11.244863. bioRxiv. 2020. PMID: 32803198 Free PMC article. Updated. Preprint.
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics.
Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Pillon MC, et al. Among authors: borgnia mj. Nat Commun. 2021 Jan 27;12(1):636. doi: 10.1038/s41467-020-20608-z. Nat Commun. 2021. PMID: 33504779 Free PMC article.
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Fu Y, da Fonseca Rezende E Mello J, Fleming BD, Renn A, Chen CZ, Hu X, Xu M, Gorshkov K, Hanson Q, Zheng W, Lee EM, Perera L, Petrovich R, Pradhan M, Eastman RT, Itkin Z, Stanley TB, Hsu A, Dandey V, Sharma K, Gillette W, Taylor T, Ramakrishnan N, Perkins S, Esposito D, Oh E, Susumu K, Wolak M, Ferrer M, Hall MD, Borgnia MJ, Simeonov A. Fu Y, et al. Among authors: borgnia mj. PLoS One. 2022 Aug 10;17(8):e0272364. doi: 10.1371/journal.pone.0272364. eCollection 2022. PLoS One. 2022. PMID: 35947606 Free PMC article.
Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Kocaman S, Lo YH, Krahn JM, Sobhany M, Dandey VP, Petrovich ML, Etigunta SK, Williams JG, Deterding LJ, Borgnia MJ, Stanley RE. Kocaman S, et al. Among authors: borgnia mj. PNAS Nexus. 2022 Jul 21;1(4):pgac118. doi: 10.1093/pnasnexus/pgac118. eCollection 2022 Sep. PNAS Nexus. 2022. PMID: 36090660 Free PMC article.
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