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The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs.
Herchenröther A, Gossen S, Friedrich T, Reim A, Daus N, Diegmüller F, Leers J, Sani HM, Gerstner S, Schwarz L, Stellmacher I, Szymkowiak LV, Nist A, Stiewe T, Borggrefe T, Mann M, Mackay JP, Bartkuhn M, Borchers A, Lan J, Hake SB. Herchenröther A, et al. Among authors: borggrefe t. Nat Commun. 2023 Jan 28;14(1):472. doi: 10.1038/s41467-023-36114-x. Nat Commun. 2023. PMID: 36709316 Free PMC article.
Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response.
Giaimo BD, Ferrante F, Vallejo DM, Hein K, Gutierrez-Perez I, Nist A, Stiewe T, Mittler G, Herold S, Zimmermann T, Bartkuhn M, Schwarz P, Oswald F, Dominguez M, Borggrefe T. Giaimo BD, et al. Among authors: borggrefe t. Nucleic Acids Res. 2018 Sep 19;46(16):8197-8215. doi: 10.1093/nar/gky551. Nucleic Acids Res. 2018. PMID: 29986055 Free PMC article.
The histone variant H2A.Z in gene regulation.
Giaimo BD, Ferrante F, Herchenröther A, Hake SB, Borggrefe T. Giaimo BD, et al. Among authors: borggrefe t. Epigenetics Chromatin. 2019 Jun 14;12(1):37. doi: 10.1186/s13072-019-0274-9. Epigenetics Chromatin. 2019. PMID: 31200754 Free PMC article. Review.
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Diéguez-Hurtado R, Kato K, Giaimo BD, Nieminen-Kelhä M, Arf H, Ferrante F, Bartkuhn M, Zimmermann T, Bixel MG, Eilken HM, Adams S, Borggrefe T, Vajkoczy P, Adams RH. Diéguez-Hurtado R, et al. Among authors: borggrefe t. Nat Commun. 2019 Jun 27;10(1):2817. doi: 10.1038/s41467-019-10643-w. Nat Commun. 2019. PMID: 31249304 Free PMC article.
HDAC3 functions as a positive regulator in Notch signal transduction.
Ferrante F, Giaimo BD, Bartkuhn M, Zimmermann T, Close V, Mertens D, Nist A, Stiewe T, Meier-Soelch J, Kracht M, Just S, Klöble P, Oswald F, Borggrefe T. Ferrante F, et al. Among authors: borggrefe t. Nucleic Acids Res. 2020 Apr 17;48(7):3496-3512. doi: 10.1093/nar/gkaa088. Nucleic Acids Res. 2020. PMID: 32107550 Free PMC article.
SPEN is required for Xist upregulation during initiation of X chromosome inactivation.
Robert-Finestra T, Tan BF, Mira-Bontenbal H, Timmers E, Gontan C, Merzouk S, Giaimo BD, Dossin F, van IJcken WFJ, Martens JWM, Borggrefe T, Heard E, Gribnau J. Robert-Finestra T, et al. Among authors: borggrefe t. Nat Commun. 2021 Dec 1;12(1):7000. doi: 10.1038/s41467-021-27294-5. Nat Commun. 2021. PMID: 34853312 Free PMC article.
Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics.
Ferrante F, Giaimo BD, Friedrich T, Sugino T, Mertens D, Kugler S, Gahr BM, Just S, Pan L, Bartkuhn M, Potente M, Oswald F, Borggrefe T. Ferrante F, et al. Among authors: borggrefe t. Cell Death Dis. 2022 Jul 12;13(7):600. doi: 10.1038/s41419-022-05052-9. Cell Death Dis. 2022. PMID: 35821235 Free PMC article.
Notch-dependent and -independent functions of transcription factor RBPJ.
Friedrich T, Ferrante F, Pioger L, Nist A, Stiewe T, Andrau JC, Bartkuhn M, Giaimo BD, Borggrefe T. Friedrich T, et al. Among authors: borggrefe t. Nucleic Acids Res. 2022 Aug 12;50(14):7925-7937. doi: 10.1093/nar/gkac601. Nucleic Acids Res. 2022. PMID: 35848919 Free PMC article.
66 results