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Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.
Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, Adams RH. Pitulescu ME, et al. Among authors: borggrefe t. Nat Cell Biol. 2017 Aug;19(8):915-927. doi: 10.1038/ncb3555. Epub 2017 Jul 17. Nat Cell Biol. 2017. PMID: 28714968
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.
Oswald F, Rodriguez P, Giaimo BD, Antonello ZA, Mira L, Mittler G, Thiel VN, Collins KJ, Tabaja N, Cizelsky W, Rothe M, Kühl SJ, Kühl M, Ferrante F, Hein K, Kovall RA, Dominguez M, Borggrefe T. Oswald F, et al. Among authors: borggrefe t. Nucleic Acids Res. 2016 Jun 2;44(10):4703-20. doi: 10.1093/nar/gkw105. Epub 2016 Feb 23. Nucleic Acids Res. 2016. PMID: 26912830 Free PMC article.
Dynamic chromatin regulation at Notch target genes.
Giaimo BD, Oswald F, Borggrefe T. Giaimo BD, et al. Among authors: borggrefe t. Transcription. 2017 Jan;8(1):61-66. doi: 10.1080/21541264.2016.1265702. Epub 2016 Dec 27. Transcription. 2017. PMID: 28027012 Free PMC article.
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.
Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba-Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF. Xu T, et al. Among authors: borggrefe t. EMBO J. 2017 Nov 2;36(21):3232-3249. doi: 10.15252/embj.201796525. Epub 2017 Oct 13. EMBO J. 2017. PMID: 29030483 Free PMC article.
Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells.
Zakrzewicz D, Didiasova M, Krüger M, Giaimo BD, Borggrefe T, Mieth M, Hocke AC, Zakrzewicz A, Schaefer L, Preissner KT, Wygrecka M. Zakrzewicz D, et al. Among authors: borggrefe t. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1816-1827. doi: 10.1016/j.bbadis.2018.02.021. Epub 2018 Mar 2. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29501774 Free article.
66 results