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Panobinostat (LBH589) increase survival in adult xenografic model of acute lymphoblastic leukemia with t(4;11) but promotes antagonistic effects in combination with MTX and 6MP.
Moreno DA, Junior HLR, Laranjeira ABA, Cruzeiro GAV, Borges KS, Salomão KB, Ramalho FS, Yunes JA, Silva CLA, Rego EM, Scrideli CA, Tone LG. Moreno DA, et al. Among authors: borges ks. Med Oncol. 2022 Sep 29;39(12):216. doi: 10.1007/s12032-022-01813-w. Med Oncol. 2022. PMID: 36175721
The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.
Andrade AF, Borges KS, Suazo VK, Geron L, Corrêa CA, Castro-Gamero AM, de Vasconcelos EJ, de Oliveira RS, Neder L, Yunes JA, Dos Santos Aguiar S, Scrideli CA, Tone LG. Andrade AF, et al. Among authors: borges ks. Invest New Drugs. 2017 Feb;35(1):26-36. doi: 10.1007/s10637-016-0401-4. Epub 2016 Oct 26. Invest New Drugs. 2017. PMID: 27785591
Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells.
Castro-Gamero AM, Borges KS, da Silva Silveira V, Lira RC, de Paula Gomes Queiroz R, Valera FC, Scrideli CA, Umezawa K, Tone LG. Castro-Gamero AM, et al. Among authors: borges ks. Anticancer Drugs. 2012 Jul;23(6):638-50. doi: 10.1097/CAD.0b013e328350e835. Anticancer Drugs. 2012. PMID: 22382389
Expression profile of apoptosis-related genes in childhood adrenocortical tumors: low level of expression of BCL2 and TNF genes suggests a poor prognosis.
Lorea CF, Moreno DA, Borges KS, Martinelli CE Jr, Antonini SR, de Castro M, Tucci S Jr, Neder L, Ramalho LN, Cardinalli I, Seidinger AL, Mastellaro MJ, Yunes JA, Brandalise SR, Tone LG, Scrideli CA. Lorea CF, et al. Among authors: borges ks. Eur J Endocrinol. 2012 Aug;167(2):199-208. doi: 10.1530/EJE-12-0183. Epub 2012 May 22. Eur J Endocrinol. 2012. PMID: 22619347
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells.
Castro-Gamero AM, Borges KS, Moreno DA, Suazo VK, Fujinami MM, de Paula Gomes Queiroz R, de Oliveira HF, Carlotti CG Jr, Scrideli CA, Tone LG. Castro-Gamero AM, et al. Among authors: borges ks. Invest New Drugs. 2013 Aug;31(4):858-70. doi: 10.1007/s10637-012-9917-4. Epub 2013 Jan 9. Invest New Drugs. 2013. PMID: 23299390
32 results