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Human fasting plasma concentrations of vitamin E and carotenoids, and their association with genetic variants in apo C-III, cholesteryl ester transfer protein, hepatic lipase, intestinal fatty acid binding protein and microsomal triacylglycerol transfer protein.
Borel P, Moussa M, Reboul E, Lyan B, Defoort C, Vincent-Baudry S, Maillot M, Gastaldi M, Darmon M, Portugal H, Lairon D, Planells R. Borel P, et al. Br J Nutr. 2009 Mar;101(5):680-7. doi: 10.1017/S0007114508030754. Epub 2008 Jul 29. Br J Nutr. 2009. PMID: 18662427
Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans.
Lecompte S, Szabo de Edelenyi F, Goumidi L, Maiani G, Moschonis G, Widhalm K, Molnár D, Kafatos A, Spinneker A, Breidenassel C, Dallongeville J, Meirhaeghe A, Borel P. Lecompte S, et al. Among authors: borel p. Am J Clin Nutr. 2011 Mar;93(3):644-51. doi: 10.3945/ajcn.110.004176. Epub 2011 Jan 12. Am J Clin Nutr. 2011. PMID: 21228269 Free article. Clinical Trial.
CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans.
Borel P, Lietz G, Goncalves A, Szabo de Edelenyi F, Lecompte S, Curtis P, Goumidi L, Caslake MJ, Miles EA, Packard C, Calder PC, Mathers JC, Minihane AM, Tourniaire F, Kesse-Guyot E, Galan P, Hercberg S, Breidenassel C, González Gross M, Moussa M, Meirhaeghe A, Reboul E. Borel P, et al. J Nutr. 2013 Apr;143(4):448-56. doi: 10.3945/jn.112.172734. Epub 2013 Feb 20. J Nutr. 2013. PMID: 23427331 Free article. Clinical Trial.
The distribution and relative hydrolysis of tocopheryl acetate in the different matrices coexisting in the lumen of the small intestine during digestion could explain its low bioavailability.
Desmarchelier C, Tourniaire F, Prévéraud DP, Samson-Kremser C, Crenon I, Rosilio V, Borel P. Desmarchelier C, et al. Among authors: borel p. Mol Nutr Food Res. 2013 Jul;57(7):1237-45. doi: 10.1002/mnfr.201200720. Epub 2013 Mar 21. Mol Nutr Food Res. 2013. PMID: 23520193
189 results