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Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, Morretta E, Ricci P, Urbani G, Monti MC, Biagioli M, Distrutti E, Catalanotti B, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: bordoni m. Front Oncol. 2023 Mar 14;13:1140730. doi: 10.3389/fonc.2023.1140730. eCollection 2023. Front Oncol. 2023. PMID: 36998446 Free PMC article.
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions.
Biagioli M, Carino A, Fiorucci C, Annunziato G, Marchianò S, Bordoni M, Roselli R, Giorgio CD, Castiglione F, Ricci P, Bruno A, Faccini A, Distrutti E, Baldoni M, Costantino G, Fiorucci S. Biagioli M, et al. Among authors: bordoni m. Nutrients. 2019 Aug 7;11(8):1820. doi: 10.3390/nu11081820. Nutrients. 2019. PMID: 31394746 Free PMC article.
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
Carino A, Biagioli M, Marchianò S, Fiorucci C, Bordoni M, Roselli R, Di Giorgio C, Baldoni M, Ricci P, Monti MC, Morretta E, Zampella A, Distrutti E, Fiorucci S. Carino A, et al. Among authors: bordoni m. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158733. doi: 10.1016/j.bbalip.2020.158733. Epub 2020 May 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32371093
GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis.
Marino S, Finamore C, Biagioli M, Carino A, Marchianò S, Roselli R, Giorgio CD, Bordoni M, Di Leva FS, Novellino E, Cassiano C, Limongelli V, Zampella A, Festa C, Fiorucci S. Marino S, et al. Among authors: bordoni m. ACS Med Chem Lett. 2020 Mar 2;11(5):818-824. doi: 10.1021/acsmedchemlett.9b00636. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435390 Free PMC article.
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction.
Biagioli M, Marchianò S, Roselli R, Di Giorgio C, Bellini R, Bordoni M, Gidari A, Sabbatini S, Francisci D, Fiorillo B, Catalanotti B, Distrutti E, Carino A, Zampella A, Costantino G, Fiorucci S. Biagioli M, et al. Among authors: bordoni m. Biochem Pharmacol. 2021 Jun;188:114564. doi: 10.1016/j.bcp.2021.114564. Epub 2021 Apr 17. Biochem Pharmacol. 2021. PMID: 33872570 Free PMC article.
81 results