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Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.
Cancer Cell. 2013 Apr 15;23(4):477-88. doi: 10.1016/j.ccr.2013.02.019.
Cancer Cell. 2013.
PMID: 23597562
Free article.
N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Boldron C, Besse A, Bordes MF, Tissandié S, Yvon X, Gau B, Badorc A, Rousseaux T, Barré G, Meneyrol J, Zech G, Nazare M, Fossey V, Pflieger AM, Bonnet-Lignon S, Millet L, Briot C, Dol F, Hérault JP, Savi P, Lassalle G, Delesque N, Herbert JM, Bono F.
Boldron C, et al. Among authors: bordes mf.
J Med Chem. 2014 Sep 11;57(17):7293-316. doi: 10.1021/jm500588w. Epub 2014 Aug 25.
J Med Chem. 2014.
PMID: 25075638
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New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.
Badorc A, Bordes MF, de Cointet P, Savi P, Bernat A, Lalé A, Petitou M, Maffrand JP, Herbert JM.
Badorc A, et al. Among authors: bordes mf.
J Med Chem. 1997 Oct 10;40(21):3393-401. doi: 10.1021/jm970240y.
J Med Chem. 1997.
PMID: 9341914
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SR 121787, a new orally active fibrinogen receptor antagonist.
Savi P, Badorc A, Lalé A, Bordes MF, Bornia J, Labouret C, Bernat A, de Cointet P, Hoffmann P, Maffrand JP, Herbert JM.
Savi P, et al. Among authors: bordes mf.
Thromb Haemost. 1998 Sep;80(3):469-76.
Thromb Haemost. 1998.
PMID: 9759629
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