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Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes.
Ter Braak B, Niemeijer M, Boon R, Parmentier C, Baze A, Richert L, Huppelschoten S, Wink S, Verfaillie C, van de Water B. Ter Braak B, et al. Among authors: boon r. Toxicol In Vitro. 2021 Jun;73:105107. doi: 10.1016/j.tiv.2021.105107. Epub 2021 Feb 3. Toxicol In Vitro. 2021. PMID: 33545341 Free article.
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.
Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM. Ordovás L, et al. Among authors: boon r. Stem Cell Reports. 2015 Nov 10;5(5):918-931. doi: 10.1016/j.stemcr.2015.09.004. Epub 2015 Oct 8. Stem Cell Reports. 2015. PMID: 26455413 Free PMC article.
Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.
Manesia JK, Xu Z, Broekaert D, Boon R, van Vliet A, Eelen G, Vanwelden T, Stegen S, Van Gastel N, Pascual-Montano A, Fendt SM, Carmeliet G, Carmeliet P, Khurana S, Verfaillie CM. Manesia JK, et al. Among authors: boon r. Stem Cell Res. 2015 Nov;15(3):715-721. doi: 10.1016/j.scr.2015.11.001. Epub 2015 Nov 9. Stem Cell Res. 2015. PMID: 26599326 Free article.
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.
Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, Christen S, Dong X, Kuenen S, Voordeckers K, Verstreken P, Cassiman D, Vermeersch P, Verfaillie C, Hiller K, Fendt SM. Lorendeau D, et al. Among authors: boon r. Metab Eng. 2017 Sep;43(Pt B):187-197. doi: 10.1016/j.ymben.2016.11.005. Epub 2016 Nov 12. Metab Eng. 2017. PMID: 27847310
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, Ordovás L, Patel A, Welters M, Vanwelden T, Geens N, Tricot T, Benoy V, Steyaert J, Lefebvre-Omar C, Boesmans W, Jarpe M, Sterneckert J, Wegner F, Petri S, Bohl D, Vanden Berghe P, Robberecht W, Van Damme P, Verfaillie C, Van Den Bosch L. Guo W, et al. Among authors: boon r. Nat Commun. 2017 Oct 11;8(1):861. doi: 10.1038/s41467-017-00911-y. Nat Commun. 2017. PMID: 29021520 Free PMC article.
Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.
Pistoni M, Helsen N, Vanhove J, Boon R, Xu Z, Ordovas L, Verfaillie CM. Pistoni M, et al. Among authors: boon r. PLoS One. 2017 Nov 1;12(11):e0186884. doi: 10.1371/journal.pone.0186884. eCollection 2017. PLoS One. 2017. PMID: 29091973 Free PMC article.
264 results