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Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice.
Singh A, Mommers-Elshof ETAM, Vijver SV, Jansen JHM, Gonder S, Lebbink RJ, Bihan D, Farndale RW, Boon L, Langermann S, Leusen JHW, Flies D, Meyaard L, Pascoal Ramos MI. Singh A, et al. Among authors: boon l. Cancer Immunol Immunother. 2024 Jan 18;73(1):16. doi: 10.1007/s00262-023-03600-6. Cancer Immunol Immunother. 2024. PMID: 38236251 Free PMC article.
Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer.
Boelaars K, Goossens-Kruijssen L, Wang D, de Winde CM, Rodriguez E, Lindijer D, Springer B, van der Haar Àvila I, de Haas A, Wehry L, Boon L, Mebius RE, van Montfoort N, Wuhrer M, den Haan JMM, van Vliet SJ, van Kooyk Y. Boelaars K, et al. Among authors: boon l. J Immunother Cancer. 2023 Nov;11(11):e007805. doi: 10.1136/jitc-2023-007805. J Immunother Cancer. 2023. PMID: 37940346 Free PMC article.
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells.
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, Felsberg J, Sabel MC, Rapp M, Knobbe-Thomsen C, Liu P, Zhao L, Kepp O, Boon L, Tejpar S, Borst J, Kroemer G, Schlenner S, De Vleeschouwer S, Sorg RV, Garg AD. Sprooten J, et al. Among authors: boon l. Cell Rep Med. 2024 Jan 16;5(1):101377. doi: 10.1016/j.xcrm.2023.101377. Cell Rep Med. 2024. PMID: 38232703 Free PMC article.
Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor.
Ge T, Phung AL, Jhala G, Trivedi P, Principe N, De George DJ, Pappas EG, Litwak S, Sanz-Villanueva L, Catterall T, Fynch S, Boon L, Kay TW, Chee J, Krishnamurthy B, Thomas HE. Ge T, et al. Among authors: boon l. Clin Transl Immunology. 2022 Oct 30;11(11):e1425. doi: 10.1002/cti2.1425. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36325490 Free PMC article.
SHP-2 and PD-1-SHP-2 signaling regulate myeloid cell differentiation and antitumor responses.
Christofides A, Katopodi XL, Cao C, Karagkouni D, Aliazis K, Yenyuwadee S, Aksoylar HI, Pal R, Mahmoud MAA, Strauss L, Tijaro-Ovalle NM, Boon L, Asara J, Vlachos IS, Patsoukis N, Boussiotis VA. Christofides A, et al. Among authors: boon l. Nat Immunol. 2023 Jan;24(1):55-68. doi: 10.1038/s41590-022-01385-x. Epub 2022 Dec 29. Nat Immunol. 2023. PMID: 36581713 Free PMC article.
582 results