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Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine.
Kokkinou M, Irvine EE, Bonsall DR, Natesan S, Wells LA, Smith M, Glegola J, Paul EJ, Tossell K, Veronese M, Khadayate S, Dedic N, Hopkins SC, Ungless MA, Withers DJ, Howes OD. Kokkinou M, et al. Among authors: bonsall dr. Mol Psychiatry. 2021 Jun;26(6):2562-2576. doi: 10.1038/s41380-020-0740-6. Epub 2020 May 7. Mol Psychiatry. 2021. PMID: 32382134 Free PMC article.
Evaluation of Intraperitoneal [18F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity.
Halff EF, Natesan S, Bonsall DR, Veronese M, Garcia-Hidalgo A, Kokkinou M, Tang SP, Riggall LJ, Gunn RN, Irvine EE, Withers DJ, Wells LA, Howes OD. Halff EF, et al. Among authors: bonsall dr. Mol Imaging. 2022 Oct 28;2022:4419221. doi: 10.1155/2022/4419221. eCollection 2022. Mol Imaging. 2022. PMID: 36721730 Free PMC article.
Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study.
Petty A, Garcia-Hidalgo A, Halff EF, Natesan S, Withers DJ, Irvine EE, Kokkinou M, Wells LA, Bonsall DR, Tang SP, Veronese M, Howes OD. Petty A, et al. Among authors: bonsall dr. Mol Imaging Biol. 2023 Dec;25(6):1054-1062. doi: 10.1007/s11307-023-01865-y. Epub 2023 Oct 23. Mol Imaging Biol. 2023. PMID: 37872462 Free PMC article.
Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
Bernard-Gauthier V, Mossine AV, Knight A, Patnaik D, Zhao WN, Cheng C, Krishnan HS, Xuan LL, Chindavong PS, Reis SA, Chen JM, Shao X, Stauff J, Arteaga J, Sherman P, Salem N, Bonsall D, Amaral B, Varlow C, Wells L, Martarello L, Patel S, Liang SH, Kurumbail RG, Haggarty SJ, Scott PJH, Vasdev N. Bernard-Gauthier V, et al. J Med Chem. 2019 Nov 14;62(21):9600-9617. doi: 10.1021/acs.jmedchem.9b01030. Epub 2019 Oct 21. J Med Chem. 2019. PMID: 31535859 Free PMC article.
15 results