Bonomo RA - Search Results

1

New β-Lactamase Inhibitors in the Clinic.

Papp-Wallace KM, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. Infect Dis Clin North Am. 2016 Jun;30(2):441-464. doi: 10.1016/j.idc.2016.02.007. Infect Dis Clin North Am. 2016. PMID: 27208767 Free PMC article. Review.

2

Molecular genetics of resistance to both ceftazidime and beta-lactam-beta-lactamase inhibitor combinations in Klebsiella pneumoniae and in vivo response to beta-lactam therapy.

Rice LB, Carias LL, Bonomo RA, Shlaes DM. Rice LB, et al. Among authors: bonomo ra. J Infect Dis. 1996 Jan;173(1):151-8. doi: 10.1093/infdis/173.1.151. J Infect Dis. 1996. PMID: 8537652

3

OHIO-1 beta-lactamase mutants: the Arg244Ser mutant and resistance to beta-lactams and beta-lactamase inhibitors.

Lin S, Thomas M, Mark S, Anderson V, Bonomo RA. Lin S, et al. Among authors: bonomo ra. Biochim Biophys Acta. 1999 Jun 15;1432(1):125-36. doi: 10.1016/s0167-4838(99)00025-4. Biochim Biophys Acta. 1999. PMID: 10366735

4

Beta-lactamases: a survey of protein diversity.

Helfand MS, Bonomo RA. Helfand MS, et al. Among authors: bonomo ra. Curr Drug Targets Infect Disord. 2003 Mar;3(1):9-23. doi: 10.2174/1568005033342181. Curr Drug Targets Infect Disord. 2003. PMID: 12570729 Review.

5

Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.

Helfand MS, Bethel CR, Hujer AM, Hujer KM, Anderson VE, Bonomo RA. Helfand MS, et al. Among authors: bonomo ra. J Biol Chem. 2003 Dec 26;278(52):52724-9. doi: 10.1074/jbc.M306059200. Epub 2003 Oct 8. J Biol Chem. 2003. PMID: 14534312 Free article.

6

Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.

Bethel CR, Hujer AM, Helfand MS, Bonomo RA. Bethel CR, et al. Among authors: bonomo ra. FEMS Microbiol Lett. 2004 May 1;234(1):99-103. doi: 10.1016/j.femsle.2004.03.025. FEMS Microbiol Lett. 2004. PMID: 15109726

7

Use of novel boronic acid transition state inhibitors to probe substrate affinity in SHV-type extended-spectrum beta-lactamases.

Thomson JM, Prati F, Bethel CR, Bonomo RA. Thomson JM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2007 Apr;51(4):1577-9. doi: 10.1128/AAC.01293-06. Epub 2007 Jan 12. Antimicrob Agents Chemother. 2007. PMID: 17220410 Free PMC article.

8

Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.

Helfand MS, Taracila MA, Totir MA, Bonomo RA, Buynak JD, van den Akker F, Carey PR. Helfand MS, et al. Among authors: bonomo ra. Biochemistry. 2007 Jul 24;46(29):8689-99. doi: 10.1021/bi700581q. Epub 2007 Jun 27. Biochemistry. 2007. PMID: 17595114

9

Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.

Thomson JM, Distler AM, Bonomo RA. Thomson JM, et al. Among authors: bonomo ra. Biochemistry. 2007 Oct 9;46(40):11361-8. doi: 10.1021/bi700792a. Epub 2007 Sep 12. Biochemistry. 2007. PMID: 17848099

10

Inhibition of OXA-1 beta-lactamase by penems.

Bethel CR, Distler AM, Ruszczycky MW, Carey MP, Carey PR, Hujer AM, Taracila M, Helfand MS, Thomson JM, Kalp M, Anderson VE, Leonard DA, Hujer KM, Abe T, Venkatesan AM, Mansour TS, Bonomo RA. Bethel CR, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2008 Sep;52(9):3135-43. doi: 10.1128/AAC.01677-07. Epub 2008 Jun 16. Antimicrob Agents Chemother. 2008. PMID: 18559643 Free PMC article.

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