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The azaindole framework in the design of kinase inhibitors.
Mérour JY, Buron F, Plé K, Bonnet P, Routier S. Mérour JY, et al. Among authors: bonnet p. Molecules. 2014 Nov 28;19(12):19935-79. doi: 10.3390/molecules191219935. Molecules. 2014. PMID: 25460315 Free PMC article. Review.
Structural investigation of B-Raf paradox breaker and inducer inhibitors.
Arora R, Di Michele M, Stes E, Vandermarliere E, Martens L, Gevaert K, Van Heerde E, Linders JT, Brehmer D, Jacoby E, Bonnet P. Arora R, et al. Among authors: bonnet p. J Med Chem. 2015 Feb 26;58(4):1818-31. doi: 10.1021/jm501667n. Epub 2015 Feb 10. J Med Chem. 2015. PMID: 25611072
Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.
Boulahjar R, Ouach A, Bourg S, Bonnet P, Lozach O, Meijer L, Guguen-Guillouzo C, Le Guevel R, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: bonnet p. Eur J Med Chem. 2015 Aug 28;101:274-87. doi: 10.1016/j.ejmech.2015.06.046. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26142492 Free article.
Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules.
Di Michele M, Stes E, Vandermarliere E, Arora R, Astorga-Wells J, Vandenbussche J, van Heerde E, Zubarev R, Bonnet P, Linders JT, Jacoby E, Brehmer D, Martens L, Gevaert K. Di Michele M, et al. Among authors: bonnet p. J Proteome Res. 2015 Oct 2;14(10):4179-93. doi: 10.1021/acs.jproteome.5b00282. Epub 2015 Aug 25. J Proteome Res. 2015. PMID: 26293246
Correction to Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors.
Arora R, Di Michele M, Stes E, Vandermarliere E, Martens L, Gevaert K, Van Heerde E, Linders JT, Brehmer D, Jacoby E, Bonnet P. Arora R, et al. Among authors: bonnet p. J Med Chem. 2016 Jul 28;59(14):6973. doi: 10.1021/acs.jmedchem.6b00941. Epub 2016 Jul 6. J Med Chem. 2016. PMID: 27385554 No abstract available.
730 results