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A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.
Bradfield JP, Vogelezang S, Felix JF, Chesi A, Helgeland Ø, Horikoshi M, Karhunen V, Lowry E, Cousminer DL, Ahluwalia TS, Thiering E, Boh ET, Zafarmand MH, Vilor-Tejedor N, Wang CA, Joro R, Chen Z, Gauderman WJ, Pitkänen N, Parra EJ, Fernandez-Rhodes L, Alyass A, Monnereau C, Curtin JA, Have CT, McCormack SE, Hollensted M, Frithioff-Bøjsøe C, Valladares-Salgado A, Peralta-Romero J, Teo YY, Standl M, Leinonen JT, Holm JC, Peters T, Vioque J, Vrijheid M, Simpson A, Custovic A, Vaudel M, Canouil M, Lindi V, Atalay M, Kähönen M, Raitakari OT, van Schaik BDC, Berkowitz RI, Cole SA, Voruganti VS, Wang Y, Highland HM, Comuzzie AG, Butte NF, Justice AE, Gahagan S, Blanco E, Lehtimäki T, Lakka TA, Hebebrand J, Bonnefond A, Grarup N, Froguel P, Lyytikäinen LP, Cruz M, Kobes S, Hanson RL, Zemel BS, Hinney A, Teo KK, Meyre D, North KE, Gilliland FD, Bisgaard H, Bustamante M, Bonnelykke K, Pennell CE, Rivadeneira F, Uitterlinden AG, Baier LJ, Vrijkotte TGM, Heinrich J, Sørensen TIA, Saw SM, Pedersen O, Hansen T, Eriksson J, Widén E, McCarthy MI, Njølstad PR, Power C, Hyppönen E, Sebert S, Brown CD, Järvelin MR, Timpson NJ, Johansson S, Hakonarson H, Jaddoe VWV; Early Growth Genetics Con… See abstract for full author list ➔ Bradfield JP, et al. Among authors: bonnelykke k. Hum Mol Genet. 2019 Oct 1;28(19):3327-3338. doi: 10.1093/hmg/ddz161. Hum Mol Genet. 2019. PMID: 31504550 Free PMC article.
Age dependent systemic exposure to inhaled salbutamol.
Bønnelykke K, Jespersen JJ, Bisgaard H. Bønnelykke K, et al. Br J Clin Pharmacol. 2007 Aug;64(2):241-4. doi: 10.1111/j.1365-2125.2007.02868.x. Epub 2007 Mar 1. Br J Clin Pharmacol. 2007. PMID: 17335545 Free PMC article. Clinical Trial.
Extrapolating evidence beyond age groups.
Bisgaard H, Bønnelykke K. Bisgaard H, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2008 Apr;121(4):1066-7; author reply 1067-8. doi: 10.1016/j.jaci.2008.01.068. Epub 2008 Mar 5. J Allergy Clin Immunol. 2008. PMID: 18325574 No abstract available.
Sensitization does not develop in utero.
Bønnelykke K, Pipper CB, Bisgaard H. Bønnelykke K, et al. J Allergy Clin Immunol. 2008 Mar;121(3):646-51. doi: 10.1016/j.jaci.2007.12.1149. J Allergy Clin Immunol. 2008. PMID: 18328892
Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood.
Bisgaard H, Bønnelykke K, Sleiman PM, Brasholt M, Chawes B, Kreiner-Møller E, Stage M, Kim C, Tavendale R, Baty F, Pipper CB, Palmer CN, Hakonarsson H. Bisgaard H, et al. Among authors: bonnelykke k. Am J Respir Crit Care Med. 2009 Feb 1;179(3):179-85. doi: 10.1164/rccm.200809-1436OC. Epub 2008 Nov 21. Am J Respir Crit Care Med. 2009. PMID: 19029000
Variants of DENND1B associated with asthma in children.
Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Sleiman PM, et al. Among authors: bonnelykke k. N Engl J Med. 2010 Jan 7;362(1):36-44. doi: 10.1056/NEJMoa0901867. Epub 2009 Dec 23. N Engl J Med. 2010. PMID: 20032318 Free article.
Long-term studies of the natural history of asthma in childhood.
Bisgaard H, Bønnelykke K. Bisgaard H, et al. Among authors: bonnelykke k. J Allergy Clin Immunol. 2010 Aug;126(2):187-97; quiz 198-9. doi: 10.1016/j.jaci.2010.07.011. J Allergy Clin Immunol. 2010. PMID: 20688204 Review.
291 results