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Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway.
Teinturier R, Luo Y, Decaussin-Petrucci M, Vlaeminck-Guillem V, Vacherot F, Firlej V, Bonnavion R, Abou Ziki R, Gherardi S, Goddard I, Gadot N, Bertolino P, Le Romancer M, Zhang CX. Teinturier R, et al. Among authors: bonnavion r. Oncogene. 2021 Feb;40(6):1118-1127. doi: 10.1038/s41388-020-01589-1. Epub 2020 Dec 15. Oncogene. 2021. PMID: 33323967
Both PAX4 and MAFA are expressed in a substantial proportion of normal human pancreatic alpha cells and deregulated in patients with type 2 diabetes.
Bonnavion R, Jaafar R, Kerr-Conte J, Assade F, van Stralen E, Leteurtre E, Pouponnot C, Gargani S, Pattou F, Bertolino P, Cordier-Bussat M, Lu J, Zhang CX. Bonnavion R, et al. PLoS One. 2013 Aug 27;8(8):e72194. doi: 10.1371/journal.pone.0072194. eCollection 2013. PLoS One. 2013. PMID: 24013263 Free PMC article.
Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.
Hamze Z, Vercherat C, Bernigaud-Lacheretz A, Bazzi W, Bonnavion R, Lu J, Calender A, Pouponnot C, Bertolino P, Roche C, Stein R, Scoazec JY, Zhang CX, Cordier-Bussat M. Hamze Z, et al. Among authors: bonnavion r. Endocr Relat Cancer. 2013 Oct 24;20(6):833-48. doi: 10.1530/ERC-13-0164. Print 2013 Dec. Endocr Relat Cancer. 2013. PMID: 24157940 Free PMC article.
Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors.
Bonnavion R, Teinturier R, Jaafar R, Ripoche D, Leteurtre E, Chen YJ, Rehfeld JF, Lepinasse F, Hervieu V, Pattou F, Vantyghem MC, Scoazec JY, Bertolino P, Zhang CX. Bonnavion R, et al. Mol Cell Biol. 2015 Oct;35(19):3274-83. doi: 10.1128/MCB.00302-15. Epub 2015 Jul 13. Mol Cell Biol. 2015. PMID: 26169832 Free PMC article.
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