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Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Bollu LR, Bommi PV, Monsen PJ, Zhai L, Lauing KL, Bell A, Kim M, Ladomersky E, Yang X, Platanias LC, Matei DE, Bonini MG, Munshi HG, Hashizume R, Wu JD, Zhang B, James CD, Chen P, Kocherginsky M, Horbinski C, Cameron MD, Grigorescu AA, Yamini B, Lukas RV, Schiltz GE, Wainwright DA. Bollu LR, et al. Among authors: bonini mg. J Med Chem. 2022 Dec 8;65(23):15642-15662. doi: 10.1021/acs.jmedchem.2c00771. Epub 2022 Nov 21. J Med Chem. 2022. PMID: 36410047 Free PMC article.
Lessons learned in the practice of community-based participatory research with community partner collaboration in study design and implementation: the community scientist model.
Morrell MA, Willis TR, Brown DR, O'Brian CA, Post SL, Woloschak GE, Bonini MG, Paunesku T, Popovic J, Manning TM, Henley C, Girotti J, Rogers R, Velásquez C, López J, Glenn J, Simon MA. Morrell MA, et al. Among authors: bonini mg. Cancer Causes Control. 2023 Jul;34(7):621-624. doi: 10.1007/s10552-023-01699-7. Epub 2023 Apr 21. Cancer Causes Control. 2023. PMID: 37081154
Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance.
Palma FR, Coelho DR, Pulakanti K, Sakiyama MJ, Huang Y, Ogata FT, Danes JM, Meyer A, Furdui CM, Spitz DR, Gomes AP, Gantner BN, Rao S, Backman V, Bonini MG. Palma FR, et al. Among authors: bonini mg. Cell Rep. 2024 Mar 26;43(3):113897. doi: 10.1016/j.celrep.2024.113897. Epub 2024 Mar 16. Cell Rep. 2024. PMID: 38493478 Free article.
ROS production by mitochondria: function or dysfunction?
Palma FR, Gantner BN, Sakiyama MJ, Kayzuka C, Shukla S, Lacchini R, Cunniff B, Bonini MG. Palma FR, et al. Among authors: bonini mg. Oncogene. 2024 Jan;43(5):295-303. doi: 10.1038/s41388-023-02907-z. Epub 2023 Dec 11. Oncogene. 2024. PMID: 38081963 Review.
Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
Coelho DR, Palma FR, Paviani V, He C, Danes JM, Huang Y, Calado JCP, Hart PC, Furdui CM, Poole LB, Schipma MJ, Bonini MG. Coelho DR, et al. Among authors: bonini mg. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2110348119. doi: 10.1073/pnas.2110348119. Epub 2022 Jul 14. Proc Natl Acad Sci U S A. 2022. PMID: 35858297 Free PMC article.
Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.
Jiang Y, Krantz S, Qin X, Li S, Gunasekara H, Kim YM, Zimnicka A, Bae M, Ma K, Toth PT, Hu Y, Shajahan-Haq AN, Patel HH, Gentile S, Bonini MG, Rehman J, Liu Y, Minshall RD. Jiang Y, et al. Among authors: bonini mg. Redox Biol. 2022 Jun;52:102304. doi: 10.1016/j.redox.2022.102304. Epub 2022 Apr 6. Redox Biol. 2022. PMID: 35413643 Free PMC article.
AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism.
Palma FR, Ratti BA, Paviani V, Coelho DR, Miguel R, Danes JM, Zaichik SV, de Abreu AL, Silva SO, Chen Y, Silverstein RL, Karan U, Jones DP, Bonini MG. Palma FR, et al. Among authors: bonini mg. Oncogene. 2021 Sep;40(36):5455-5467. doi: 10.1038/s41388-021-01943-x. Epub 2021 Jul 21. Oncogene. 2021. PMID: 34290400 Free PMC article.
107 results