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Lowered quality of life in mood disorders is associated with increased neuro-oxidative stress and basal thyroid-stimulating hormone levels and use of anticonvulsant mood stabilizers.
Nunes CS, Maes M, Roomruangwong C, Moraes JB, Bonifacio KL, Vargas HO, Barbosa DS, Anderson G, de Melo LGP, Drozdstoj S, Moreira E, Carvalho AF, Nunes SOV. Nunes CS, et al. Among authors: bonifacio kl. J Eval Clin Pract. 2018 Aug;24(4):869-878. doi: 10.1111/jep.12918. Epub 2018 Apr 17. J Eval Clin Pract. 2018. PMID: 29665163
Lowered PON1 activities are strongly associated with depression and bipolar disorder, recurrence of (hypo)mania and depression, increased disability and lowered quality of life.
Moreira EG, Correia DG, Bonifácio KL, Moraes JB, Cavicchioli FL, Nunes CS, Nunes SOV, Vargas HO, Barbosa DS, Maes M. Moreira EG, et al. Among authors: bonifacio kl. World J Biol Psychiatry. 2019 Jun;20(5):368-380. doi: 10.1080/15622975.2017.1322219. Epub 2017 May 30. World J Biol Psychiatry. 2019. PMID: 28441923
In major affective disorders, early life trauma predict increased nitro-oxidative stress, lipid peroxidation and protein oxidation and recurrence of major affective disorders, suicidal behaviors and a lowered quality of life.
Moraes JB, Maes M, Roomruangwong C, Bonifacio KL, Barbosa DS, Vargas HO, Anderson G, Kubera M, Carvalho AF, Nunes SOV. Moraes JB, et al. Among authors: bonifacio kl. Metab Brain Dis. 2018 Aug;33(4):1081-1096. doi: 10.1007/s11011-018-0209-3. Epub 2018 Mar 14. Metab Brain Dis. 2018. PMID: 29542039
Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses.
Maes M, Bonifacio KL, Morelli NR, Vargas HO, Moreira EG, St Stoyanov D, Barbosa DS, Carvalho AF, Nunes SOV. Maes M, et al. Among authors: bonifacio kl. Neurotox Res. 2018 Oct;34(3):489-510. doi: 10.1007/s12640-018-9906-2. Epub 2018 May 7. Neurotox Res. 2018. PMID: 29736827
25 results