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Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses.
Darnotuk ES, Siniavin AE, Shastina NS, Luyksaar SI, Inshakova AM, Bondareva NE, Zolotov SA, Lubenec NL, Sheremet AB, Logunov DY, Zigangirova NA, Gushchin VA, Gintsburg AL. Darnotuk ES, et al. Among authors: bondareva ne. Pharmaceuticals (Basel). 2023 Dec 26;17(1):35. doi: 10.3390/ph17010035. Pharmaceuticals (Basel). 2023. PMID: 38256869 Free PMC article.
Pharmacokinetics, quorum-sensing signal molecules and tryptophan-related metabolomics of the novel anti-virulence drug Fluorothiazinon in a Pseudomonas aeruginosa-induced pneumonia murine model.
Savitskii MV, Moskaleva NE, Brito A, Zigangirova NA, Soloveva AV, Sheremet AB, Bondareva NE, Lubenec NL, Kuznetsov RM, Samoylov VM, Tagliaro F, Appolonova SA. Savitskii MV, et al. Among authors: bondareva ne. J Pharm Biomed Anal. 2023 Nov 30;236:115739. doi: 10.1016/j.jpba.2023.115739. Epub 2023 Sep 21. J Pharm Biomed Anal. 2023. PMID: 37778200
Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits.
Savitskii MV, Moskaleva NE, Brito A, Markin PA, Zigangirova NA, Soloveva AV, Sheremet AB, Bondareva NE, Lubenec NL, Tagliaro F, Tarasov VV, Tatzhikova KA, Appolonova SA. Savitskii MV, et al. Among authors: bondareva ne. J Antibiot (Tokyo). 2024 Mar 15. doi: 10.1038/s41429-024-00719-1. Online ahead of print. J Antibiot (Tokyo). 2024. PMID: 38491136
Association with Monoclonal Antibody Promotes Intracellular Delivery of Lycopene.
Petyaev IM, Zigangirova NA, Tsibezov VV, Morgunova EY, Bondareva NE, Kyle NH, Bashmakov YK. Petyaev IM, et al. Among authors: bondareva ne. Monoclon Antib Immunodiagn Immunother. 2018 Jun;37(3):147-152. doi: 10.1089/mab.2018.0010. Epub 2018 Jun 14. Monoclon Antib Immunodiagn Immunother. 2018. PMID: 29901419
A novel antivirulent compound fluorothiazinone inhibits Klebsiella pneumoniae biofilm in vitro and suppresses model pneumonia.
Tsarenko SV, Zigangirova NA, Soloveva AV, Bondareva NE, Koroleva EA, Sheremet AB, Kapotina LN, Shevlyagina NV, Andreevskaya SG, Zhukhovitsky VG, Filimonova EV, Gintsburg AL. Tsarenko SV, et al. Among authors: bondareva ne. J Antibiot (Tokyo). 2023 Jul;76(7):397-405. doi: 10.1038/s41429-023-00621-2. Epub 2023 Apr 21. J Antibiot (Tokyo). 2023. PMID: 37085670
Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection.
Koroleva EA, Soloveva AV, Morgunova EY, Kapotina LN, Luyksaar SI, Luyksaar SV, Bondareva NE, Nelubina SA, Lubenec NL, Zigangirova NA, Gintsburg AL. Koroleva EA, et al. Among authors: bondareva ne. J Antibiot (Tokyo). 2023 May;76(5):279-290. doi: 10.1038/s41429-023-00602-5. Epub 2023 Mar 15. J Antibiot (Tokyo). 2023. PMID: 36922636