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A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-cell Stemness Shows Enhanced CAR T-cell Efficacy in Preclinical and Early Clinical Development.
Dickinson MJ, Barba P, Jäger U, Shah NN, Blaise D, Briones J, Shune L, Boissel N, Bondanza A, Mariconti L, Marchal AL, Quinn DS, Yang J, Price A, Sohoni A, Treanor LM, Orlando EJ, Mataraza J, Davis J, Lu D, Zhu X, Engels B, Moutouh-de Parseval L, Brogdon JL, Moschetta M, Flinn IW. Dickinson MJ, et al. Among authors: bondanza a. Cancer Discov. 2023 Sep 6;13(9):1982-1997. doi: 10.1158/2159-8290.CD-22-1276. Cancer Discov. 2023. PMID: 37249512 Free PMC article.
Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses.
Raccosta L, Marinozzi M, Costantini S, Maggioni D, Ferreira LM, Corna G, Zordan P, Sorice A, Farinello D, Bianchessi S, Riba M, Lazarevic D, Provero P, Mack M, Bondanza A, Nalvarte I, Gustafsson JA, Ranzani V, De Sanctis F, Ugel S, Baron S, Lobaccaro JA, Pontini L, Pacciarini M, Traversari C, Pagani M, Bronte V, Sitia G, Antonson P, Brendolan A, Budillon A, Russo V. Raccosta L, et al. Among authors: bondanza a. Cell Death Dis. 2023 Feb 15;14(2):129. doi: 10.1038/s41419-023-05620-7. Cell Death Dis. 2023. PMID: 36792589 Free PMC article.
CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome.
Arcangeli S, Bove C, Mezzanotte C, Camisa B, Falcone L, Manfredi F, Bezzecchi E, El Khoury R, Norata R, Sanvito F, Ponzoni M, Greco B, Moresco MA, Carrabba MG, Ciceri F, Bonini C, Bondanza A, Casucci M. Arcangeli S, et al. Among authors: bondanza a. J Clin Invest. 2022 Jun 15;132(12):e150807. doi: 10.1172/JCI150807. J Clin Invest. 2022. PMID: 35503659 Free PMC article.
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies.
Greco B, Malacarne V, De Girardi F, Scotti GM, Manfredi F, Angelino E, Sirini C, Camisa B, Falcone L, Moresco MA, Paolella K, Di Bono M, Norata R, Sanvito F, Arcangeli S, Doglioni C, Ciceri F, Bonini C, Graziani A, Bondanza A, Casucci M. Greco B, et al. Among authors: bondanza a. Sci Transl Med. 2022 Jan 19;14(628):eabg3072. doi: 10.1126/scitranslmed.abg3072. Epub 2022 Jan 19. Sci Transl Med. 2022. PMID: 35044789
Mother Donors Improve Outcomes after HLA Haploidentical Transplantation: A Study by the Cellular Therapy and Immunobiology Working Party of the European Society for Blood and Marrow Transplantation.
Ruggeri L, Eikema DJ, Bondanza A, Noviello M, van Biezen A, de Wreede LC, Crucitti L, Vago L, Ciardelli S, Bader P, Koc Y, Locatelli F, Veelken JH, Gruhn B, Evans P, Chabannon C, Toubert A, Velardi A. Ruggeri L, et al. Among authors: bondanza a. Transplant Cell Ther. 2022 Apr;28(4):206.e1-206.e6. doi: 10.1016/j.jtct.2022.01.001. Epub 2022 Jan 10. Transplant Cell Ther. 2022. PMID: 35017118 Free article.
Manufacturing of Human Tissues as off-the-Shelf Grafts Programmed to Induce Regeneration.
Pigeot S, Klein T, Gullotta F, Dupard SJ, Garcia Garcia A, García-García A, Prithiviraj S, Lorenzo P, Filippi M, Jaquiery C, Kouba L, Asnaghi MA, Raina DB, Dasen B, Isaksson H, Önnerfjord P, Tägil M, Bondanza A, Martin I, Bourgine PE. Pigeot S, et al. Among authors: bondanza a. Adv Mater. 2021 Oct;33(43):e2103737. doi: 10.1002/adma.202103737. Epub 2021 Sep 5. Adv Mater. 2021. PMID: 34486186
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis.
Biavasco R, Lettera E, Giannetti K, Gilioli D, Beretta S, Conti A, Scala S, Cesana D, Gallina P, Norelli M, Basso-Ricci L, Bondanza A, Cavalli G, Ponzoni M, Dagna L, Doglioni C, Aiuti A, Merelli I, Di Micco R, Montini E. Biavasco R, et al. Among authors: bondanza a. Nat Commun. 2021 Jul 27;12(1):4559. doi: 10.1038/s41467-021-24876-1. Nat Commun. 2021. PMID: 34315896 Free PMC article.
90 results