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Probing benzenesulfonamide-thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II.
Gamal MA, Fahim SH, Giovannuzzi S, Fouad MA, Bonardi A, Gratteri P, Supuran CT, Hassan GS. Gamal MA, et al. Among authors: bonardi a. Eur J Med Chem. 2024 May 5;271:116434. doi: 10.1016/j.ejmech.2024.116434. Epub 2024 Apr 20. Eur J Med Chem. 2024. PMID: 38653067
Dual Inhibitors of Brain Carbonic Anhydrases and Monoamine Oxidase-B Efficiently Protect against Amyloid-β-Induced Neuronal Toxicity, Oxidative Stress, and Mitochondrial Dysfunction.
Giovannuzzi S, Chavarria D, Provensi G, Leri M, Bucciantini M, Carradori S, Bonardi A, Gratteri P, Borges F, Nocentini A, Supuran CT. Giovannuzzi S, et al. Among authors: bonardi a. J Med Chem. 2024 Mar 14;67(5):4170-4193. doi: 10.1021/acs.jmedchem.4c00045. Epub 2024 Mar 4. J Med Chem. 2024. PMID: 38436571
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies.
Begines P, Bonardi A, Nocentini A, Gratteri P, Giovannuzzi S, Ronca R, Tavani C, Luisa Massardi M, López Ó, Supuran CT. Begines P, et al. Among authors: bonardi a. Bioorg Med Chem. 2023 Oct 30;94:117467. doi: 10.1016/j.bmc.2023.117467. Epub 2023 Sep 7. Bioorg Med Chem. 2023. PMID: 37722299
99 results