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Page 1
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility.
Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher A. Amaral EP, et al. Among authors: bomfim ccb. Nat Microbiol. 2024 Jan;9(1):120-135. doi: 10.1038/s41564-023-01523-7. Epub 2023 Dec 8. Nat Microbiol. 2024. PMID: 38066332 Free PMC article.
Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis.
Bomfim CCB, Fisher L, Amaral EP, Mittereder L, McCann K, Correa AAS, Namasivayam S, Swamydas M, Moayeri M, Weiss JM, Chari R, McVicar DW, Costa DL, D'Império Lima MR, Sher A. Bomfim CCB, et al. Front Cell Infect Microbiol. 2022 May 2;12:862582. doi: 10.3389/fcimb.2022.862582. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35586249 Free PMC article.
P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis.
Santiago-Carvalho I, de Almeida-Santos G, Bomfim CCB, de Souza PC, Silva JCSE, de Melo BMS, Amaral EP, Cione MVP, Lasunskaia E, Hirata MH, Alves-Filho JCF, Nakaya HI, Alvarez JM, D'Império Lima MR. Santiago-Carvalho I, et al. Among authors: bomfim ccb. Front Cell Infect Microbiol. 2021 May 5;11:672472. doi: 10.3389/fcimb.2021.672472. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34026666 Free PMC article.
Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas.
Souza De Lima D, Bomfim CCB, Leal VNC, Reis EC, Soares JLS, Fernandes FP, Amaral EP, Loures FV, Ogusku MM, Lima MRD, Sadahiro A, Pontillo A. Souza De Lima D, et al. Among authors: bomfim ccb. Front Immunol. 2020 Oct 21;11:550624. doi: 10.3389/fimmu.2020.550624. eCollection 2020. Front Immunol. 2020. PMID: 33193317 Free PMC article.
Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.
Amaral EP, Ribeiro SC, Lanes VR, Almeida FM, de Andrade MR, Bomfim CC, Salles EM, Bortoluci KR, Coutinho-Silva R, Hirata MH, Alvarez JM, Lasunskaia EB, D'Império-Lima MR. Amaral EP, et al. PLoS Pathog. 2014 Jul 3;10(7):e1004188. doi: 10.1371/journal.ppat.1004188. eCollection 2014 Jul. PLoS Pathog. 2014. PMID: 24991816 Free PMC article.