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Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4.
Lamaa D, Lin HP, Zig L, Bauvais C, Bollot G, Bignon J, Levaique H, Pamlard O, Dubois J, Ouaissi M, Souce M, Kasselouri A, Saller F, Borgel D, Jayat-Vignoles C, Al-Mouhammad H, Feuillard J, Benihoud K, Alami M, Hamze A. Lamaa D, et al. Among authors: bollot g. J Med Chem. 2018 Aug 9;61(15):6574-6591. doi: 10.1021/acs.jmedchem.8b00050. Epub 2018 Jul 26. J Med Chem. 2018. PMID: 30004697
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A. Hauguel C, et al. Among authors: bollot g. Eur J Med Chem. 2022 Oct 5;240:114573. doi: 10.1016/j.ejmech.2022.114573. Epub 2022 Jul 1. Eur J Med Chem. 2022. PMID: 35797900 Free article.
YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis.
Kretov DA, Clément MJ, Lambert G, Durand D, Lyabin DN, Bollot G, Bauvais C, Samsonova A, Budkina K, Maroun RC, Hamon L, Bouhss A, Lescop E, Toma F, Curmi PA, Maucuer A, Ovchinnikov LP, Pastré D. Kretov DA, et al. Among authors: bollot g. Nucleic Acids Res. 2019 Apr 8;47(6):3127-3141. doi: 10.1093/nar/gky1303. Nucleic Acids Res. 2019. PMID: 30605522 Free PMC article.
Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase.
Sari-Hassoun M, Clement MJ, Hamdi I, Bollot G, Bauvais C, Joshi V, Toma F, Burgo A, Cailleret M, Rosales-Hernández MC, Macias Pérez ME, Chabane-Sari D, Curmi PA. Sari-Hassoun M, et al. Among authors: bollot g. Biochem Pharmacol. 2016 Feb 15;102:45-63. doi: 10.1016/j.bcp.2015.12.013. Epub 2015 Dec 18. Biochem Pharmacol. 2016. PMID: 26707799
Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.
Blondel S, Egesipe AL, Picardi P, Jaskowiak AL, Notarnicola M, Ragot J, Tournois J, Le Corf A, Brinon B, Poydenot P, Georges P, Navarro C, Pitrez PR, Ferreira L, Bollot G, Bauvais C, Laustriat D, Mejat A, De Sandre-Giovannoli A, Levy N, Bifulco M, Peschanski M, Nissan X. Blondel S, et al. Among authors: bollot g. Cell Death Dis. 2016 Feb 18;7(2):e2105. doi: 10.1038/cddis.2015.374. Cell Death Dis. 2016. PMID: 26890144 Free PMC article.
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