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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, Jaenisch R. Lyssiotis CA, et al. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8912-7. doi: 10.1073/pnas.0903860106. Epub 2009 May 15. Proc Natl Acad Sci U S A. 2009. PMID: 19447925 Free PMC article.
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, Jaenisch R, Schultz PG. Staerk J, et al. Angew Chem Int Ed Engl. 2011 Jun 14;50(25):5734-6. doi: 10.1002/anie.201101042. Epub 2011 May 5. Angew Chem Int Ed Engl. 2011. PMID: 21547985 Free PMC article. No abstract available.
Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate.
Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, Kazane SA, Young TS, Tremblay MS. Yu S, et al. Among authors: bollong mj. Mol Ther. 2016 Dec;24(12):2078-2089. doi: 10.1038/mt.2016.175. Epub 2016 Oct 12. Mol Ther. 2016. PMID: 27731313 Free PMC article.
A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers.
Bollong MJ, Pietilä M, Pearson AD, Sarkar TR, Ahmad I, Soundararajan R, Lyssiotis CA, Mani SA, Schultz PG, Lairson LL. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912. doi: 10.1073/pnas.1716009114. Epub 2017 Oct 30. Proc Natl Acad Sci U S A. 2017. PMID: 29087350 Free PMC article.
A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer.
Lucki NC, Villa GR, Vergani N, Bollong MJ, Beyer BA, Lee JW, Anglin JL, Spangenberg SH, Chin EN, Sharma A, Johnson K, Sander PN, Gordon P, Skirboll SL, Wurdak H, Schultz PG, Mischel PS, Lairson LL. Lucki NC, et al. Among authors: bollong mj. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6435-6440. doi: 10.1073/pnas.1816626116. Epub 2019 Mar 7. Proc Natl Acad Sci U S A. 2019. PMID: 30846550 Free PMC article.
Small-Molecule Stimulators of NRF1 Transcriptional Activity.
Iaconelli J, Ibrahim L, Chen E, Hull M, Schultz PG, Bollong MJ. Iaconelli J, et al. Among authors: bollong mj. Chembiochem. 2020 Jul 1;21(13):1816-1819. doi: 10.1002/cbic.201900487. Epub 2019 Nov 8. Chembiochem. 2020. PMID: 31596542
33 results