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G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
Biomolecules. 2023 Oct 20;13(10):1552. doi: 10.3390/biom13101552.
Biomolecules. 2023.
PMID: 37892234
Free PMC article.
Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder.
Boateng CA, Nilson AN, Placide R, Pham ML, Jakobs FM, Boldizsar N, McIntosh S, Stallings LS, Korankyi IV, Kelshikar S, Shah N, Panasis D, Muccilli A, Ladik M, Maslonka B, McBride C, Sanchez MX, Akca E, Alkhatib M, Saez J, Nguyen C, Kurtyan E, DePierro J, Crowthers R, Brunt D, Bonifazi A, Newman AH, Rais R, Slusher BS, Free RB, Sibley DR, Stewart KD, Wu C, Hemby SE, Keck TM.
Boateng CA, et al. Among authors: boldizsar n.
J Med Chem. 2023 Sep 14;66(17):12141-12162. doi: 10.1021/acs.jmedchem.3c00734. Epub 2023 Aug 30.
J Med Chem. 2023.
PMID: 37646374
Free PMC article.
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Phosphorylation barcodes direct biased chemokine signaling at CXCR3.
Eiger DS, Smith JS, Shi T, Stepniewski TM, Tsai CF, Honeycutt C, Boldizsar N, Gardner J, Nicora CD, Moghieb AM, Kawakami K, Choi I, Hicks C, Zheng K, Warman A, Alagesan P, Knape NM, Huang O, Silverman JD, Smith RD, Inoue A, Selent J, Jacobs JM, Rajagopal S.
Eiger DS, et al. Among authors: boldizsar n.
Cell Chem Biol. 2023 Apr 20;30(4):362-382.e8. doi: 10.1016/j.chembiol.2023.03.006. Epub 2023 Apr 7.
Cell Chem Biol. 2023.
PMID: 37030291
Free PMC article.
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Phosphorylation barcodes direct biased chemokine signaling at CXCR3.
Eiger DS, Smith JS, Shi T, Stepniewski TM, Tsai CF, Honeycutt C, Boldizsar N, Gardner J, Nicora CD, Moghieb AM, Kawakami K, Choi I, Zheng K, Warman A, Alagesan P, Knape NM, Huang O, Silverman JD, Smith RD, Inoue A, Selent J, Jacobs JM, Rajagopal S.
Eiger DS, et al. Among authors: boldizsar n.
bioRxiv [Preprint]. 2023 Mar 14:2023.03.14.532634. doi: 10.1101/2023.03.14.532634.
bioRxiv. 2023.
PMID: 36993369
Free PMC article.
Updated.
Preprint.
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Identification and Characterization of ML321: A Novel and Highly Selective D2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity.
Free RB, Nilson AN, Boldizsar NM, Doyle TB, Rodriguiz RM, Pogorelov VM, Machino M, Lee KH, Bertz JW, Xu J, Lim HD, Dulcey AE, Mach RH, Woods JH, Lane JR, Shi L, Marugan JJ, Wetsel WC, Sibley DR.
Free RB, et al. Among authors: boldizsar nm.
ACS Pharmacol Transl Sci. 2022 Dec 30;6(1):151-170. doi: 10.1021/acsptsci.2c00202. eCollection 2023 Jan 13.
ACS Pharmacol Transl Sci. 2022.
PMID: 36654757
Free PMC article.
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Location bias contributes to functionally selective responses of biased CXCR3 agonists.
Eiger DS, Boldizsar N, Honeycutt CC, Gardner J, Kirchner S, Hicks C, Choi I, Pham U, Zheng K, Warman A, Smith JS, Zhang JY, Rajagopal S.
Eiger DS, et al. Among authors: boldizsar n.
Nat Commun. 2022 Oct 4;13(1):5846. doi: 10.1038/s41467-022-33569-2.
Nat Commun. 2022.
PMID: 36195635
Free PMC article.
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Biased agonists of the chemokine receptor CXCR3 differentially signal through Gαi:β-arrestin complexes.
Zheng K, Smith JS, Eiger DS, Warman A, Choi I, Honeycutt CC, Boldizsar N, Gundry JN, Pack TF, Inoue A, Caron MG, Rajagopal S.
Zheng K, et al. Among authors: boldizsar n.
Sci Signal. 2022 Mar 22;15(726):eabg5203. doi: 10.1126/scisignal.abg5203. Epub 2022 Mar 22.
Sci Signal. 2022.
PMID: 35316095
Free PMC article.
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Biased agonism at chemokine receptors.
Eiger DS, Boldizsar N, Honeycutt CC, Gardner J, Rajagopal S.
Eiger DS, et al. Among authors: boldizsar n.
Cell Signal. 2021 Feb;78:109862. doi: 10.1016/j.cellsig.2020.109862. Epub 2020 Nov 27.
Cell Signal. 2021.
PMID: 33249087
Free PMC article.
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