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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.
Bol GM, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, Levine A, Irving A, Korz D, Tantravedi S, Heerma van Voss MR, Gabrielson K, Bordt EA, Polster BM, Cope L, van der Groep P, Kondaskar A, Rudek MA, Hosmane RS, van der Wall E, van Diest PJ, Tran PT, Raman V. Bol GM, et al. EMBO Mol Med. 2015 May;7(5):648-69. doi: 10.15252/emmm.201404368. EMBO Mol Med. 2015. PMID: 25820276 Free PMC article.
DDX3, a potential target for cancer treatment.
Bol GM, Xie M, Raman V. Bol GM, et al. Mol Cancer. 2015 Nov 5;14:188. doi: 10.1186/s12943-015-0461-7. Mol Cancer. 2015. PMID: 26541825 Free PMC article. Review.
RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3.
Xie M, Vesuna F, Tantravedi S, Bol GM, Heerma van Voss MR, Nugent K, Malek R, Gabrielson K, van Diest PJ, Tran PT, Raman V. Xie M, et al. Among authors: bol gm. Cancer Res. 2016 Nov 1;76(21):6340-6350. doi: 10.1158/0008-5472.CAN-16-0440. Epub 2016 Sep 12. Cancer Res. 2016. PMID: 27634756 Free PMC article.
Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer.
Heerma van Voss MR, Vesuna F, Bol GM, Meeldijk J, Raman A, Offerhaus GJ, Buerger H, Patel AH, van der Wall E, van Diest PJ, Raman V. Heerma van Voss MR, et al. Among authors: bol gm. Onco Targets Ther. 2017 Jul 17;10:3501-3513. doi: 10.2147/OTT.S140639. eCollection 2017. Onco Targets Ther. 2017. PMID: 28761359 Free PMC article.
Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment.
Heerma van Voss MR, Vesuna F, Bol GM, Afzal J, Tantravedi S, Bergman Y, Kammers K, Lehar M, Malek R, Ballew M, Ter Hoeve N, Abou D, Thorek D, Berlinicke C, Yazdankhah M, Sinha D, Le A, Abrahams R, Tran PT, van Diest PJ, Raman V. Heerma van Voss MR, et al. Among authors: bol gm. Oncogene. 2018 Jan 4;37(1):63-74. doi: 10.1038/onc.2017.308. Epub 2017 Sep 4. Oncogene. 2018. PMID: 28869602 Free PMC article.
23 results