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Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior.
Bijata M, Bączyńska E, Müller FE, Bijata K, Masternak J, Krzystyniak A, Szewczyk B, Siwiec M, Antoniuk S, Roszkowska M, Figiel I, Magnowska M, Olszyński KH, Wardak AD, Hogendorf A, Ruszczycki B, Gorinski N, Labus J, Stępień T, Tarka S, Bojarski AJ, Tokarski K, Filipkowski RK, Ponimaskin E, Wlodarczyk J. Bijata M, et al. Among authors: bojarski aj. Cell Rep. 2022 Mar 15;38(11):110532. doi: 10.1016/j.celrep.2022.110532. Cell Rep. 2022. PMID: 35294881 Free article.
Pyrano[2,3,4-cd]indole as a Scaffold for Selective Nonbasic 5-HT6R Ligands.
Staroń J, Mordalski S, Warszycki D, Satała G, Hogendorf A, Bojarski AJ. Staroń J, et al. Among authors: bojarski aj. ACS Med Chem Lett. 2017 Mar 27;8(4):390-394. doi: 10.1021/acsmedchemlett.6b00482. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435524 Free PMC article.
Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol.
Hogendorf AS, Hogendorf A, Kurczab R, Satała G, Lenda T, Walczak M, Latacz G, Handzlik J, Kieć-Kononowicz K, Wierońska JM, Woźniak M, Cieślik P, Bugno R, Staroń J, Bojarski AJ. Hogendorf AS, et al. Among authors: bojarski aj. Sci Rep. 2017 May 4;7(1):1444. doi: 10.1038/s41598-017-00822-4. Sci Rep. 2017. PMID: 28473721 Free PMC article.
Search for a 5-CT alternative. In vitro and in vivo evaluation of novel pharmacological tools: 3-(1-alkyl-1H-imidazol-5-yl)-1H-indole-5-carboxamides, low-basicity 5-HT7 receptor agonists.
Latacz G, Hogendorf AS, Hogendorf A, Lubelska A, Wierońska JM, Woźniak M, Cieślik P, Kieć-Kononowicz K, Handzlik J, Bojarski AJ. Latacz G, et al. Among authors: bojarski aj. Medchemcomm. 2018 Sep 25;9(11):1882-1890. doi: 10.1039/c8md00313k. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30568756 Free PMC article.
Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers.
Hogendorf AS, Hogendorf A, Popiołek-Barczyk K, Ciechanowska A, Mika J, Satała G, Walczak M, Latacz G, Handzlik J, Kieć-Kononowicz K, Ponimaskin E, Schade S, Zeug A, Bijata M, Kubicki M, Kurczab R, Lenda T, Staroń J, Bugno R, Duszyńska B, Pilarski B, Bojarski AJ. Hogendorf AS, et al. Among authors: bojarski aj. Eur J Med Chem. 2019 May 15;170:261-275. doi: 10.1016/j.ejmech.2019.03.017. Epub 2019 Mar 11. Eur J Med Chem. 2019. PMID: 30904783
How can fluorine directly and indirectly affect the hydrogen bonding in molecular systems? - A case study for monofluoroanilines.
Pietruś W, Kurczab R, Kafel R, Machalska E, Kalinowska-Tłuścik J, Hogendorf A, Żylewski M, Baranska M, Bojarski AJ. Pietruś W, et al. Among authors: bojarski aj. Spectrochim Acta A Mol Biomol Spectrosc. 2021 May 5;252:119536. doi: 10.1016/j.saa.2021.119536. Epub 2021 Feb 3. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 33588362
N-Skatyltryptamines-Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential.
Hogendorf A, Hogendorf AS, Kurczab R, Satała G, Szewczyk B, Cieślik P, Latacz G, Handzlik J, Lenda T, Kaczorowska K, Staroń J, Bugno R, Duszyńska B, Bojarski AJ. Hogendorf A, et al. Among authors: bojarski aj. Molecules. 2021 Jul 29;26(15):4605. doi: 10.3390/molecules26154605. Molecules. 2021. PMID: 34361754 Free PMC article.
234 results