Boj SF - Search Results

1

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Among authors: boj sf. Nat Med. 2017 Jan;23(1):60-68. doi: 10.1038/nm.4219. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869803

2

Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Among authors: boj sf. Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384d. Nat Med. 2017. PMID: 29117169

3

Fishing for intestinal cancer models: unraveling gastrointestinal homeostasis and tumorigenesis in zebrafish.

Faro A, Boj SF, Clevers H. Faro A, et al. Among authors: boj sf. Zebrafish. 2009 Dec;6(4):361-76. doi: 10.1089/zeb.2009.0617. Zebrafish. 2009. PMID: 19929219

4

Preclinical models of pancreatic ductal adenocarcinoma.

Hwang CI, Boj SF, Clevers H, Tuveson DA. Hwang CI, et al. Among authors: boj sf. J Pathol. 2016 Jan;238(2):197-204. doi: 10.1002/path.4651. Epub 2015 Nov 14. J Pathol. 2016. PMID: 26419819 Free PMC article. Review.

5

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M, Sato T, Hamer K, Sasaki N, Finegold MJ, Haft A, Vries RG, Grompe M, Clevers H. Huch M, et al. Among authors: boj sf. Nature. 2013 Feb 14;494(7436):247-50. doi: 10.1038/nature11826. Epub 2013 Jan 27. Nature. 2013. PMID: 23354049 Free PMC article.

6

Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids.

Putker M, Millen R, Overmeer R, Driehuis E, Zandvliet MMJM, Clevers H, Boj SF, Li QX. Putker M, et al. Among authors: boj sf. J Vis Exp. 2021 Apr 30;(170). doi: 10.3791/62495. J Vis Exp. 2021. PMID: 33999032

7

Establishment of Pancreatic Organoids from Normal Tissue and Tumors.

Driehuis E, Gracanin A, Vries RGJ, Clevers H, Boj SF. Driehuis E, et al. Among authors: boj sf. STAR Protoc. 2020 Dec 4;1(3):100192. doi: 10.1016/j.xpro.2020.100192. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377086 Free PMC article.

8

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.

Broutier L, Andersson-Rolf A, Hindley CJ, Boj SF, Clevers H, Koo BK, Huch M. Broutier L, et al. Among authors: boj sf. Nat Protoc. 2016 Sep;11(9):1724-43. doi: 10.1038/nprot.2016.097. Epub 2016 Aug 25. Nat Protoc. 2016. PMID: 27560176

9

Model organoids provide new research opportunities for ductal pancreatic cancer.

Boj SF, Hwang CI, Baker LA, Engle DD, Tuveson DA, Clevers H. Boj SF, et al. Mol Cell Oncol. 2015 Feb 23;3(1):e1014757. doi: 10.1080/23723556.2015.1014757. eCollection 2016 Jan. Mol Cell Oncol. 2015. PMID: 27308531 Free PMC article.

10

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.

Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, Drost J, Nusse R, Roose JP, Piehler J, Boj SF, Janda CY, Clevers H, Kuo CJ, Garcia KC. Miao Y, et al. Among authors: boj sf. Cell Stem Cell. 2020 Nov 5;27(5):840-851.e6. doi: 10.1016/j.stem.2020.07.020. Epub 2020 Aug 19. Cell Stem Cell. 2020. PMID: 32818433 Free PMC article.

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