The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site.
Mohan CG, Boix E, Evans HR, Nikolovski Z, Nogués MV, Cuchillo CM, Acharya KR.
Mohan CG, et al. Among authors: boix e.
Biochemistry. 2002 Oct 8;41(40):12100-6. doi: 10.1021/bi0264521.
Biochemistry. 2002.
PMID: 12356310
ECP belongs to the pancreatic ribonuclease superfamily of proteins, and the crystal structure of ECP in the unliganded form (determined previously) exhibited a conserved RNase A fold [Boix, E., et al. (1999) Biochemistry 38, 16794-16801]. We have now determined a hi …
ECP belongs to the pancreatic ribonuclease superfamily of proteins, and the crystal structure of ECP in the unliganded form (determined prev …