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Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors.
Niemeijer M, Więcek W, Fu S, Huppelschoten S, Bouwman P, Baze A, Parmentier C, Richert L, Paules RS, Bois FY, van de Water B. Niemeijer M, et al. Among authors: bois fy. Environ Health Perspect. 2024 Mar;132(3):37005. doi: 10.1289/EHP11891. Epub 2024 Mar 18. Environ Health Perspect. 2024. PMID: 38498338 Free PMC article.
Understanding Interindividual Variability in the Drug Interaction of a Highly Extracted CYP1A2 Substrate Tizanidine: Application of a Permeability-Limited Multicompartment Liver Model in a Population Based Physiologically Based Pharmacokinetic Framework.
Zhang M, Fisher C, Gardner I, Pan X, Kilford P, Bois FY, Jamei M. Zhang M, et al. Among authors: bois fy. Drug Metab Dispos. 2022 Jul;50(7):957-967. doi: 10.1124/dmd.121.000818. Epub 2022 May 3. Drug Metab Dispos. 2022. PMID: 35504655
Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks.
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY, Ciccolallo L, Craig PS, De Vries RBM, Dorne JLCM, Druwe IL, Edwards SW, Eskes C, Georgiadis M, Hartung T, Kienzler A, Kristjansson EA, Lam J, Martino L, Meek B, Morgan RL, Munoz-Guajardo I, Noyes PD, Parmelli E, Piersma A, Rooney A, Sena E, Sullivan K, Tarazona J, Terron A, Thayer K, Turner J, Verbeek J, Verloo D, Vinken M, Watford S, Whaley P, Wikoff D, Willett K, Tsaioun K. Hoffmann S, et al. Among authors: bois fy. ALTEX. 2022;39(3):499–518. doi: 10.14573/altex.2202141. Epub 2022 Mar 1. ALTEX. 2022. PMID: 35258090 Free PMC article.
A Bayesian population physiologically based pharmacokinetic absorption modeling approach to support generic drug development: application to bupropion hydrochloride oral dosage forms.
Hsieh NH, Bois FY, Tsakalozou E, Ni Z, Yoon M, Sun W, Klein M, Reisfeld B, Chiu WA. Hsieh NH, et al. Among authors: bois fy. J Pharmacokinet Pharmacodyn. 2021 Dec;48(6):893-908. doi: 10.1007/s10928-021-09778-5. Epub 2021 Sep 22. J Pharmacokinet Pharmacodyn. 2021. PMID: 34553275 Free PMC article.
118 results