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Page 1
Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model.
Brazel EB, Tan A, Neville SL, Iverson AR, Udagedara SR, Cunningham BA, Sikanyika M, De Oliveira DMP, Keller B, Bohlmann L, El-Deeb IM, Ganio K, Eijkelkamp BA, McEwan AG, von Itzstein M, Maher MJ, Walker MJ, Rosch JW, McDevitt CA. Brazel EB, et al. Among authors: bohlmann l. Cell Rep. 2022 Jan 11;38(2):110202. doi: 10.1016/j.celrep.2021.110202. Cell Rep. 2022. PMID: 35021083 Free PMC article.
Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. Among authors: bohlmann l. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis.
De Oliveira DMP, Bohlmann L, Conroy T, Jen FE, Everest-Dass A, Hansford KA, Bolisetti R, El-Deeb IM, Forde BM, Phan MD, Lacey JA, Tan A, Rivera-Hernandez T, Brouwer S, Keller N, Kidd TJ, Cork AJ, Bauer MJ, Cook GM, Davies MR, Beatson SA, Paterson DL, McEwan AG, Li J, Schembri MA, Blaskovich MAT, Jennings MP, McDevitt CA, von Itzstein M, Walker MJ. De Oliveira DMP, et al. Among authors: bohlmann l. Sci Transl Med. 2020 Nov 18;12(570):eabb3791. doi: 10.1126/scitranslmed.abb3791. Sci Transl Med. 2020. PMID: 33208501
Neurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria.
De Oliveira DMP, Keller B, Hayes AJ, Ong CY, Harbison-Price N, El-Deeb IM, Li G, Keller N, Bohlmann L, Brouwer S, Turner AG, Cork AJ, Jones TR, Paterson DL, McEwan AG, Davies MR, McDevitt CA, Itzstein MV, Walker MJ. De Oliveira DMP, et al. Among authors: bohlmann l. Antibiotics (Basel). 2022 Mar 25;11(4):449. doi: 10.3390/antibiotics11040449. Antibiotics (Basel). 2022. PMID: 35453201 Free PMC article.
Functional and structural characterization of a heparanase.
Bohlmann L, Tredwell GD, Yu X, Chang CW, Haselhorst T, Winger M, Dyason JC, Thomson RJ, Tiralongo J, Beacham IR, Blanchard H, von Itzstein M. Bohlmann L, et al. Nat Chem Biol. 2015 Dec;11(12):955-7. doi: 10.1038/nchembio.1956. Epub 2015 Nov 2. Nat Chem Biol. 2015. PMID: 26565989
Antiangiogenic platinum through glycan targeting.
Peterson EJ, Daniel AG, Katner SJ, Bohlmann L, Chang CW, Bezos A, Parish CR, von Itzstein M, Berners-Price SJ, Farrell NP. Peterson EJ, et al. Among authors: bohlmann l. Chem Sci. 2017 Jan 1;8(1):241-252. doi: 10.1039/c6sc02515c. Epub 2016 Aug 12. Chem Sci. 2017. PMID: 28451171 Free PMC article.
Proficiency testing of PIK3CA mutations in HR+/HER2-breast cancer on liquid biopsy and tissue.
Vollbrecht C, Hoffmann I, Lehmann A, Merkelbach-Bruse S, Fassunke J, Wagener-Ryczek S, Ball M, Dimitrova L, Hartmann A, Stöhr R, Erber R, Weichert W, Pfarr N, Bohlmann L, Jung A, Dietmaier W, Dietel M, Horst D, Hummel M. Vollbrecht C, et al. Among authors: bohlmann l. Virchows Arch. 2023 Apr;482(4):697-706. doi: 10.1007/s00428-022-03445-x. Epub 2022 Nov 11. Virchows Arch. 2023. PMID: 36367572 Free PMC article.
Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL.
Kumbrink J, Bohlmann L, Mamlouk S, Redmer T, Peilstöcker D, Li P, Lorenzen S, Algül H, Kasper S, Hempel D, Kaiser F, Michl M, Bartsch H, Neumann J, Klauschen F, von Bergwelt-Baildon M, Modest DP, Stahler A, Stintzing S, Jung A, Kirchner T, Schäfer R, Heinemann V, Holch JW. Kumbrink J, et al. Among authors: bohlmann l. Cancers (Basel). 2022 Jul 26;14(15):3631. doi: 10.3390/cancers14153631. Cancers (Basel). 2022. PMID: 35892888 Free PMC article.
13 results