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Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells.
Almenar-Queralt A, Merkurjev D, Kim HS, Navarro M, Ma Q, Chaves RS, Allegue C, Driscoll SP, Chen AG, Kohlnhofer B, Fong LK, Woodruff G, Mackintosh C, Bohaciakova D, Hruska-Plochan M, Tadokoro T, Young JE, El Hajj N, Dittrich M, Marsala M, Goldstein LSB, Garcia-Bassets I. Almenar-Queralt A, et al. Among authors: bohaciakova d. Nat Genet. 2019 Dec;51(12):1691-1701. doi: 10.1038/s41588-019-0526-4. Epub 2019 Nov 18. Nat Genet. 2019. PMID: 31740836 Free PMC article.
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Nemergut M, Marques SM, Uhrik L, Vanova T, Nezvedova M, Gadara DC, Jha D, Tulis J, Novakova V, Planas-Iglesias J, Kunka A, Legrand A, Hribkova H, Pospisilova V, Sedmik J, Raska J, Prokop Z, Damborsky J, Bohaciakova D, Spacil Z, Hernychova L, Bednar D, Marek M. Nemergut M, et al. Among authors: bohaciakova d. Mol Neurodegener. 2023 Jun 6;18(1):38. doi: 10.1186/s13024-023-00620-9. Mol Neurodegener. 2023. PMID: 37280636 Free PMC article.
Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development.
Vanova T, Sedmik J, Raska J, Amruz Cerna K, Taus P, Pospisilova V, Nezvedova M, Fedorova V, Kadakova S, Klimova H, Capandova M, Orviska P, Fojtik P, Bartova S, Plevova K, Spacil Z, Hribkova H, Bohaciakova D. Vanova T, et al. Among authors: bohaciakova d. Cell Rep. 2023 Nov 28;42(11):113310. doi: 10.1016/j.celrep.2023.113310. Epub 2023 Oct 20. Cell Rep. 2023. PMID: 37864790 Free article.
Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of secondary neurulation.
Fedorova V, Vanova T, Elrefae L, Pospisil J, Petrasova M, Kolajova V, Hudacova Z, Baniariova J, Barak M, Peskova L, Barta T, Kaucka M, Killinger M, Vecera J, Bernatik O, Cajanek L, Hribkova H, Bohaciakova D. Fedorova V, et al. Among authors: bohaciakova d. Stem Cell Res. 2019 Oct;40:101563. doi: 10.1016/j.scr.2019.101563. Epub 2019 Aug 29. Stem Cell Res. 2019. PMID: 31494448 Free article.
24 results