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Page 1
Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.
Andersen NJ, Nickoloff BJ, Dykema KJ, Boguslawski EA, Krivochenitser RI, Froman RE, Dawes MJ, Baker LH, Thomas DG, Kamstock DA, Kitchell BE, Furge KA, Duesbery NS. Andersen NJ, et al. Among authors: boguslawski ea. Mol Cancer Ther. 2013 Sep;12(9):1701-14. doi: 10.1158/1535-7163.MCT-12-0893. Epub 2013 Jun 26. Mol Cancer Ther. 2013. PMID: 23804705 Free PMC article.
Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.
Harlow ML, Maloney N, Roland J, Guillen Navarro MJ, Easton MK, Kitchen-Goosen SM, Boguslawski EA, Madaj ZB, Johnson BK, Bowman MJ, D'Incalci M, Winn ME, Turner L, Hostetter G, Galmarini CM, Aviles PM, Grohar PJ. Harlow ML, et al. Among authors: boguslawski ea. Cancer Res. 2016 Nov 15;76(22):6657-6668. doi: 10.1158/0008-5472.CAN-16-0568. Epub 2016 Oct 3. Cancer Res. 2016. PMID: 27697767 Free PMC article.
Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner.
Harlow ML, Chasse MH, Boguslawski EA, Sorensen KM, Gedminas JM, Kitchen-Goosen SM, Rothbart SB, Taslim C, Lessnick SL, Peck AS, Madaj ZB, Bowman MJ, Grohar PJ. Harlow ML, et al. Among authors: boguslawski ea. Clin Cancer Res. 2019 Jun 1;25(11):3417-3429. doi: 10.1158/1078-0432.CCR-18-3511. Epub 2019 Feb 5. Clin Cancer Res. 2019. PMID: 30723142 Free PMC article.
CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.
Flores G, Everett JH, Boguslawski EA, Oswald BM, Madaj ZB, Beddows I, Dikalov S, Adams M, Klumpp-Thomas CA, Kitchen-Goosen SM, Martin SE, Caplen NJ, Helman LJ, Grohar PJ. Flores G, et al. Among authors: boguslawski ea. Mol Cancer Ther. 2020 May;19(5):1183-1196. doi: 10.1158/1535-7163.MCT-19-0775. Epub 2020 Mar 3. Mol Cancer Ther. 2020. PMID: 32127464 Free PMC article.
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.
Chasse MH, Johnson BK, Boguslawski EA, Sorensen KM, Rosien JE, Kang MH, Reynolds CP, Heo L, Madaj ZB, Beddows I, Foxa GE, Kitchen-Goosen SM, Williams BO, Triche TJ Jr, Grohar PJ. Chasse MH, et al. Among authors: boguslawski ea. EMBO Mol Med. 2021 Feb 5;13(2):e12640. doi: 10.15252/emmm.202012640. Epub 2020 Dec 17. EMBO Mol Med. 2021. PMID: 33332735 Free PMC article.
19 results