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Year Number of Results
2004 1
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2007 4
2008 3
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2010 12
2011 5
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2013 1
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2018 1
2019 1
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43 results

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Page 1
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.
Cioffi CL, Raja A, Muthuraman P, Jayaraman A, Jayakumar S, Varadi A, Racz B, Petrukhin K. Cioffi CL, et al. Among authors: racz b. J Med Chem. 2021 Jul 8;64(13):9010-9041. doi: 10.1021/acs.jmedchem.1c00099. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138572 Free PMC article.
Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities.
Cioffi CL, Muthuraman P, Raja A, Varadi A, Racz B, Petrukhin K. Cioffi CL, et al. Among authors: racz b. J Med Chem. 2020 Oct 8;63(19):11054-11084. doi: 10.1021/acs.jmedchem.0c00996. Epub 2020 Sep 17. J Med Chem. 2020. PMID: 32878437 Free PMC article.
Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.
Cioffi CL, Racz B, Varadi A, Freeman EE, Conlon MP, Chen P, Zhu L, Kitchen DB, Barnes KD, Martin WH, Pearson PG, Johnson G, Blaner WS, Petrukhin K. Cioffi CL, et al. Among authors: racz b. J Med Chem. 2019 Jun 13;62(11):5470-5500. doi: 10.1021/acs.jmedchem.9b00352. Epub 2019 May 28. J Med Chem. 2019. PMID: 31079449 Free PMC article.
Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease.
Cioffi CL, Racz B, Freeman EE, Conlon MP, Chen P, Stafford DG, Schwarz DM, Zhu L, Kitchen DB, Barnes KD, Dobri N, Michelotti E, Cywin CL, Martin WH, Pearson PG, Johnson G, Petrukhin K. Cioffi CL, et al. Among authors: racz b. J Med Chem. 2015 Aug 13;58(15):5863-88. doi: 10.1021/acs.jmedchem.5b00423. Epub 2015 Aug 4. J Med Chem. 2015. PMID: 26181715 Free PMC article.
43 results