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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates.
Boeynaems S, Dorone Y, Zhuang Y, Shabardina V, Huang G, Marian A, Kim G, Sanyal A, Şen NE, Griffith D, Docampo R, Lasker K, Ruiz-Trillo I, Auburger G, Holehouse AS, Kabashi E, Lin Y, Gitler AD. Boeynaems S, et al. Mol Cell. 2023 Jun 15;83(12):2020-2034.e6. doi: 10.1016/j.molcel.2023.05.025. Epub 2023 Jun 8. Mol Cell. 2023. PMID: 37295429
Pour Some Sugar on TDP(-43).
Boeynaems S, Gitler AD. Boeynaems S, et al. Mol Cell. 2018 Sep 6;71(5):649-651. doi: 10.1016/j.molcel.2018.08.032. Mol Cell. 2018. PMID: 30193092 Free article.
Axons Gonna Ride 'til They Can't No More.
Boeynaems S, Gitler AD. Boeynaems S, et al. Neuron. 2019 Oct 23;104(2):179-181. doi: 10.1016/j.neuron.2019.09.029. Neuron. 2019. PMID: 31647889 Free article.
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity.
Gittings LM, Boeynaems S, Lightwood D, Clargo A, Topia S, Nakayama L, Troakes C, Mann DMA, Gitler AD, Lashley T, Isaacs AM. Gittings LM, et al. Among authors: boeynaems s. Acta Neuropathol. 2020 Feb;139(2):407-410. doi: 10.1007/s00401-019-02104-x. Epub 2019 Dec 12. Acta Neuropathol. 2020. PMID: 31832771 Free PMC article. No abstract available.
Designer Condensates: A Toolkit for the Biomolecular Architect.
Hastings RL, Boeynaems S. Hastings RL, et al. Among authors: boeynaems s. J Mol Biol. 2021 Jun 11;433(12):166837. doi: 10.1016/j.jmb.2021.166837. Epub 2021 Feb 1. J Mol Biol. 2021. PMID: 33539874 Free article. Review.
A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
Dorone Y, Boeynaems S, Flores E, Jin B, Hateley S, Bossi F, Lazarus E, Pennington JG, Michiels E, De Decker M, Vints K, Baatsen P, Bassel GW, Otegui MS, Holehouse AS, Exposito-Alonso M, Sukenik S, Gitler AD, Rhee SY. Dorone Y, et al. Among authors: boeynaems s. Cell. 2021 Aug 5;184(16):4284-4298.e27. doi: 10.1016/j.cell.2021.06.009. Epub 2021 Jul 6. Cell. 2021. PMID: 34233164 Free PMC article.
38 results