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A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.
Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, Shimada S, Adamski J, Busch DH, Esposito I, Klingenspor M, Wolf E, Wurst W, Gailus-Durner V, Katan M, Marschall S, Soewarto D, Wagner S, de Angelis MH. Abe K, et al. Among authors: boersma a. Arthritis Rheum. 2011 May;63(5):1301-11. doi: 10.1002/art.30280. Arthritis Rheum. 2011. PMID: 21305534 Free article.
Sperm cryopreservation and in vitro fertilization.
Marschall S, Boersma A, de Angelis MH. Marschall S, et al. Among authors: boersma a. Methods Mol Biol. 2009;530:407-20. doi: 10.1007/978-1-59745-471-1_22. Methods Mol Biol. 2009. PMID: 19266334
In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.
Klymiuk I, Kenner L, Adler T, Busch DH, Boersma A, Irmler M, Fridrich B, Gailus-Durner V, Fuchs H, Leitner N, Müller M, Kühn R, Schlederer M, Treise I, de Angelis MH, Beckers J. Klymiuk I, et al. Among authors: boersma a. PLoS One. 2012;7(10):e44609. doi: 10.1371/journal.pone.0044609. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23115618 Free PMC article.
Mitochondrial glutathione peroxidase 4 disruption causes male infertility.
Schneider M, Förster H, Boersma A, Seiler A, Wehnes H, Sinowatz F, Neumüller C, Deutsch MJ, Walch A, Hrabé de Angelis M, Wurst W, Ursini F, Roveri A, Maleszewski M, Maiorino M, Conrad M. Schneider M, et al. Among authors: boersma a. FASEB J. 2009 Sep;23(9):3233-42. doi: 10.1096/fj.09-132795. Epub 2009 May 5. FASEB J. 2009. PMID: 19417079
EGFR ligands exert diverging effects on male reproductive organs.
Schneider MR, Gratao AA, Dahlhoff M, Boersma A, Hrabé de Angelis M, Hoang-Vu C, Wolf E, Klonisch T. Schneider MR, et al. Among authors: boersma a. Exp Mol Pathol. 2010 Feb;88(1):216-8. doi: 10.1016/j.yexmp.2009.11.005. Epub 2009 Nov 25. Exp Mol Pathol. 2010. PMID: 19931240
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT, Maurer B, Prchal-Murphy M, Grausenburger R, Grundschober E, Javaheri T, Nivarthi H, Boersma A, Kolbe T, Elabd M, Halbritter F, Pencik J, Kazemi Z, Grebien F, Hengstschläger M, Kenner L, Kubicek S, Farlik M, Bock C, Valent P, Müller M, Rülicke T, Sexl V, Moriggl R. Pham HTT, et al. Among authors: boersma a. J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4. J Clin Invest. 2018. PMID: 29200404 Free PMC article.
202 results