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Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions.
Commun Biol. 2024 Apr 9;7(1):430. doi: 10.1038/s42003-024-06087-8.
Commun Biol. 2024.
PMID: 38594506
Free PMC article.
Targeting myeloid cells for cancer immunotherapy: Siglec-7/9/10/15 and their ligands.
Boelaars K, van Kooyk Y.
Boelaars K, et al.
Trends Cancer. 2024 Mar;10(3):230-241. doi: 10.1016/j.trecan.2023.11.009. Epub 2023 Dec 29.
Trends Cancer. 2024.
PMID: 38160071
Free article.
Review.
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Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer.
Boelaars K, Goossens-Kruijssen L, Wang D, de Winde CM, Rodriguez E, Lindijer D, Springer B, van der Haar Àvila I, de Haas A, Wehry L, Boon L, Mebius RE, van Montfoort N, Wuhrer M, den Haan JMM, van Vliet SJ, van Kooyk Y.
Boelaars K, et al.
J Immunother Cancer. 2023 Nov;11(11):e007805. doi: 10.1136/jitc-2023-007805.
J Immunother Cancer. 2023.
PMID: 37940346
Free PMC article.
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Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits.
Rodriguez E, Boelaars K, Brown K, Madunić K, van Ee T, Dijk F, Verheij J, Li RJE, Schetters STT, Meijer LL, Le Large TYS, Driehuis E, Clevers H, Bruijns SCM, O'Toole T, van Vliet SJ, Bijlsma MF, Wuhrer M, Kazemier G, Giovannetti E, Garcia-Vallejo JJ, van Kooyk Y.
Rodriguez E, et al. Among authors: boelaars k.
Commun Biol. 2022 Jan 11;5(1):41. doi: 10.1038/s42003-021-02934-0.
Commun Biol. 2022.
PMID: 35017635
Free PMC article.
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Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation.
Heckler M, Ali LR, Clancy-Thompson E, Qiang L, Ventre KS, Lenehan P, Roehle K, Luoma A, Boelaars K, Peters V, McCreary J, Boschert T, Wang ES, Suo S, Marangoni F, Mempel TR, Long HW, Wucherpfennig KW, Dougan M, Gray NS, Yuan GC, Goel S, Tolaney SM, Dougan SK.
Heckler M, et al. Among authors: boelaars k.
Cancer Discov. 2021 Oct;11(10):2564-2581. doi: 10.1158/2159-8290.CD-20-1540. Epub 2021 May 3.
Cancer Discov. 2021.
PMID: 33941591
Free PMC article.
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Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Rodriguez E, Boelaars K, Brown K, Eveline Li RJ, Kruijssen L, Bruijns SCM, van Ee T, Schetters STT, Crommentuijn MHW, van der Horst JC, van Grieken NCT, van Vliet SJ, Kazemier G, Giovannetti E, Garcia-Vallejo JJ, van Kooyk Y.
Rodriguez E, et al. Among authors: boelaars k.
Nat Commun. 2021 Feb 24;12(1):1270. doi: 10.1038/s41467-021-21550-4.
Nat Commun. 2021.
PMID: 33627655
Free PMC article.
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Transnuclear mice reveal Peyer's patch iNKT cells that regulate B-cell class switching to IgG1.
Clancy-Thompson E, Chen GZ, LaMarche NM, Ali LR, Jeong HJ, Crowley SJ, Boelaars K, Brenner MB, Lynch L, Dougan SK.
Clancy-Thompson E, et al. Among authors: boelaars k.
EMBO J. 2019 Jul 15;38(14):e101260. doi: 10.15252/embj.2018101260. Epub 2019 May 31.
EMBO J. 2019.
PMID: 31304630
Free PMC article.
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