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Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes.
Cancer Cell. 2014 Oct 13;26(4):549-64. doi: 10.1016/j.ccell.2014.09.003.
Cancer Cell. 2014.
PMID: 25314080
Free article.
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer.
Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Müller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T.
Bettermann K, et al. Among authors: boege y.
Cancer Cell. 2010 May 18;17(5):481-96. doi: 10.1016/j.ccr.2010.03.021.
Cancer Cell. 2010.
PMID: 20478530
Free article.
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Chronic liver inflammation and hepatocellular carcinoma: persistence matters.
Weber A, Boege Y, Reisinger F, Heikenwälder M.
Weber A, et al. Among authors: boege y.
Swiss Med Wkly. 2011 May 10;141:w13197. doi: 10.4414/smw.2011.13197. eCollection 2011.
Swiss Med Wkly. 2011.
PMID: 21557112
Free article.
Review.
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IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1.
Koppe C, Verheugd P, Gautheron J, Reisinger F, Kreggenwinkel K, Roderburg C, Quagliata L, Terracciano L, Gassler N, Tolba RH, Boege Y, Weber A, Karin M, Luedde M, Neumann UP, Weiskirchen R, Tacke F, Vucur M, Trautwein C, Lüscher B, Preisinger C, Heikenwalder M, Luedde T.
Koppe C, et al. Among authors: boege y.
Hepatology. 2016 Oct;64(4):1217-31. doi: 10.1002/hep.28723. Epub 2016 Aug 11.
Hepatology. 2016.
PMID: 27396433
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Boege Y, Malehmir M, Healy ME, Bettermann K, Lorentzen A, Vucur M, Ahuja AK, Böhm F, Mertens JC, Shimizu Y, Frick L, Remouchamps C, Mutreja K, Kähne T, Sundaravinayagam D, Wolf MJ, Rehrauer H, Koppe C, Speicher T, Padrissa-Altés S, Maire R, Schattenberg JM, Jeong JS, Liu L, Zwirner S, Boger R, Hüser N, Davis RJ, Müllhaupt B, Moch H, Schulze-Bergkamen H, Clavien PA, Werner S, Borsig L, Luther SA, Jost PJ, Weinlich R, Unger K, Behrens A, Hillert L, Dillon C, Di Virgilio M, Wallach D, Dejardin E, Zender L, Naumann M, Walczak H, Green DR, Lopes M, Lavrik I, Luedde T, Heikenwalder M, Weber A.
Boege Y, et al.
Cancer Cell. 2017 Sep 11;32(3):342-359.e10. doi: 10.1016/j.ccell.2017.08.010.
Cancer Cell. 2017.
PMID: 28898696
Free PMC article.
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MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice.
Healy ME, Boege Y, Hodder MC, Böhm F, Malehmir M, Scherr AL, Jetzer J, Chan LK, Parrotta R, Jacobs K, Clerbaux LA, Kreutzer S, Campbell A, Gilchrist E, Gilroy K, Rodewald AK, Honcharova-Biletska H, Schimmer R, Vélez K, Büeler S, Cammareri P, Kalna G, Wenning AS, McCoy KD, Gomez de Agüero M, Schulze-Bergkamen H, Klose CSN, Unger K, Macpherson AJ, Moor AE, Köhler B, Sansom OJ, Heikenwälder M, Weber A.
Healy ME, et al. Among authors: boege y.
Gastroenterology. 2020 Jul;159(1):183-199. doi: 10.1053/j.gastro.2020.03.017. Epub 2020 Mar 14.
Gastroenterology. 2020.
PMID: 32179094
Free PMC article.
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JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Müller K, Honcharova-Biletska H, Koppe C, Egger M, Chan LK, Schneider AT, Küsgens L, Böhm F, Boege Y, Healy ME, Schmitt J, Comtesse S, Castoldi M, Preisinger C, Szydlowska M, Focaccia E, Gaisa NT, Loosen SH, Jörs S, Tacke F, Roderburg C, Keitel V, Bode JG, Boor P, Davis RJ, Longerich T, Geisler F, Heikenwalder M, Weber A, Vucur M, Luedde T.
Müller K, et al. Among authors: boege y.
Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2007194118. doi: 10.1073/pnas.2007194118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33798093
Free PMC article.
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Mcl-1 deficiency in murine livers leads to nuclear polyploidisation and mitotic errors: Implications for hepatocellular carcinoma.
Clerbaux LA, Cordier P, Desboeufs N, Unger K, Leary P, Semere G, Boege Y, Chan LK, Desdouets C, Lopes M, Weber A.
Clerbaux LA, et al. Among authors: boege y.
JHEP Rep. 2023 Jul 11;5(10):100838. doi: 10.1016/j.jhepr.2023.100838. eCollection 2023 Oct.
JHEP Rep. 2023.
PMID: 37663116
Free PMC article.
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