Boeckman RK Jr - Search Results

1

The Notch pathway regulates the bone gain induced by PTH anabolic signaling.

Delgado-Calle J, McAndrews K, Wu G, Orr AL, Ferrari A, Tu X, Srinivasan V, Roodman GD, Ebetino FH, Boeckman RK Jr, Bellido T. Delgado-Calle J, et al. Among authors: boeckman rk jr. FASEB J. 2022 Mar;36(3):e22196. doi: 10.1096/fj.202101807R. FASEB J. 2022. PMID: 35137455 Free PMC article.

2

Bone-Targeted Bortezomib Inhibits Bortezomib-Resistant Multiple Myeloma in Mice by Providing Higher Levels of Bortezomib in Bone.

Tao J, Srinivasan V, Yi X, Zhao Y, Zhang H, Lin X, Zhou X, Boyce BF, Villalta PW, Ebetino FH, Ho KK, Boeckman RK Jr, Xing L. Tao J, et al. Among authors: boeckman rk jr. J Bone Miner Res. 2022 Apr;37(4):629-642. doi: 10.1002/jbmr.4496. Epub 2022 Jan 22. J Bone Miner Res. 2022. PMID: 34970782 Free PMC article.

3

Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.

Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK Jr, Roodman GD, Bellido T, Delgado-Calle J. Sabol HM, et al. Among authors: boeckman rk jr. Cancer Res. 2021 Oct 1;81(19):5102-5114. doi: 10.1158/0008-5472.CAN-21-0524. Epub 2021 Aug 4. Cancer Res. 2021. PMID: 34348968 Free PMC article.

4

Bisphosphonates for delivering drugs to bone.

Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK Jr, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell RGG, McKenna CE, Ebetino FH. Sun S, et al. Among authors: boeckman rk jr. Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10. Br J Pharmacol. 2021. PMID: 32876338 Free PMC article. Review.

5

Targeting anti-cancer agents to bone using bisphosphonates.

Xing L, Ebetino FH, Boeckman RK Jr, Srinivasan V, Tao J, Sawyer TK, Li J, Yao Z, Boyce BF. Xing L, et al. Among authors: boeckman rk jr. Bone. 2020 Sep;138:115492. doi: 10.1016/j.bone.2020.115492. Epub 2020 Jun 23. Bone. 2020. PMID: 32585321 Free PMC article. Review.

6

Targeting Bortezomib to Bone Increases Its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.

Wang H, Zhang H, Srinivasan V, Tao J, Sun W, Lin X, Wu T, Boyce BF, Ebetino FH, Boeckman RK Jr, Xing L. Wang H, et al. Among authors: boeckman rk jr. J Bone Miner Res. 2020 Feb;35(2):343-356. doi: 10.1002/jbmr.3889. Epub 2019 Nov 19. J Bone Miner Res. 2020. PMID: 31610066 Free PMC article.

7

Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice.

Wang H, Xiao L, Tao J, Srinivasan V, Boyce BF, Ebetino FH, Oyajobi BO, Boeckman RK Jr, Xing L. Wang H, et al. Among authors: boeckman rk jr. Pharmaceutics. 2018 Sep 10;10(3):154. doi: 10.3390/pharmaceutics10030154. Pharmaceutics. 2018. PMID: 30201882 Free PMC article.

8

Scalable Synthesis of (-)-Rasfonin Enabled by a Convergent Enantioselective α-Hydroxymethylation Strategy.

Boeckman RK Jr, Niziol JM, Biegasiewicz KF. Boeckman RK Jr, et al. Org Lett. 2018 Aug 17;20(16):5062-5065. doi: 10.1021/acs.orglett.8b02222. Epub 2018 Aug 3. Org Lett. 2018. PMID: 30074398

9

A Scalable Total Synthesis of (-)-Nakadomarin A.

Boeckman RK Jr, Wang H, Rugg KW, Genung NE, Chen K, Ryder TR. Boeckman RK Jr, et al. Org Lett. 2016 Dec 2;18(23):6136-6139. doi: 10.1021/acs.orglett.6b03137. Epub 2016 Nov 11. Org Lett. 2016. PMID: 27934385

10

Organocatalytic enantioselective α-hydroxymethylation of aldehydes: mechanistic aspects and optimization.

Boeckman RK Jr, Biegasiewicz KF, Tusch DJ, Miller JR. Boeckman RK Jr, et al. J Org Chem. 2015 Apr 17;80(8):4030-45. doi: 10.1021/acs.joc.5b00380. Epub 2015 Apr 3. J Org Chem. 2015. PMID: 25793648

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