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JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: bock c. Nat Immunol. 2024 May;25(5):847-859. doi: 10.1038/s41590-024-01804-1. Epub 2024 Apr 24. Nat Immunol. 2024. PMID: 38658806
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman MW, Eder T, Abdallah DI, Maurer B, Wagner C, Schönefeldt S, Spirk K, Pichler A, Pemovska T, Schweicker C, Pölöske D, Hubanic E, Jungherz D, Müller TA, Aung MMK, Orlova A, Pham HTT, Zimmel K, Krausgruber T, Bock C, Müller M, Dahlhoff M, Boersma A, Rülicke T, Fleck R, de Araujo ED, Gunning PT, Aittokallio T, Mustjoki S, Sanda T, Hartmann S, Grebien F, Hoermann G, Haferlach T, Staber PB, Neubauer HA, Look AT, Herling M, Moriggl R. Suske T, et al. Among authors: bock c. J Clin Invest. 2024 Apr 15;134(8):e168536. doi: 10.1172/JCI168536. J Clin Invest. 2024. PMID: 38618957 Free PMC article.
Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice.
Hevesi Z, Bakker J, Tretiakov EO, Adori C, Raabgrund A, Barde SS, Caramia M, Krausgruber T, Ladstätter S, Bock C, Hökfelt T, Harkany T. Hevesi Z, et al. Among authors: bock c. Nat Commun. 2024 Mar 29;15(1):2762. doi: 10.1038/s41467-024-47054-5. Nat Commun. 2024. PMID: 38553447 Free PMC article.
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual.
Kocher K, Moosmann C, Drost F, Schülein C, Irrgang P, Steininger P, Zhong J, Träger J, Spriewald B, Bock C, Busch DH, Bogdan C, Schubert B, Winkler TH, Tenbusch M, Schuster EM, Schober K. Kocher K, et al. Among authors: bock c. Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8. Epub 2024 Mar 4. Lancet Infect Dis. 2024. PMID: 38452777 No abstract available.
A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.
Kosasih HJ, Healey G, Brennan MS, Bjelosevic S, Sadras T, Jalud FB, Ibnat T, Ng AP, Mayoh C, Mao J, Tax G, Ludlow LEA, Johnstone RW, Herold MJ, Khaw SL, de Bock CE, Ekert PG. Kosasih HJ, et al. Among authors: de bock ce. Hemasphere. 2024 Feb 14;8(2):e1. doi: 10.1002/hem3.1. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435422 Free PMC article. No abstract available.
1,143 results