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Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells.
Ghelli Luserna Di Rorà A, Ghetti M, Ledda L, Ferrari A, Bocconcelli M, Padella A, Napolitano R, Fontana MC, Liverani C, Imbrogno E, Bochicchio MT, Paganelli M, Robustelli V, Sanogo S, Cerchione C, Fumagalli M, Rondoni M, Imovilli A, Musuraca G, Martinelli G, Simonetti G. Ghelli Luserna Di Rorà A, et al. Among authors: bochicchio mt. Cell Biol Toxicol. 2023 Jun;39(3):795-811. doi: 10.1007/s10565-021-09640-x. Epub 2021 Sep 14. Cell Biol Toxicol. 2023. PMID: 34519926 Free PMC article.
Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients.
Zuffa E, Franchini E, Papayannidis C, Baldazzi C, Simonetti G, Testoni N, Abbenante MC, Paolini S, Sartor C, Parisi S, Marconi G, Cattina F, Bochicchio MT, Venturi C, Ottaviani E, Cavo M, Martinelli G. Zuffa E, et al. Among authors: bochicchio mt. Oncotarget. 2015 Oct 13;6(31):31284-94. doi: 10.18632/oncotarget.5161. Oncotarget. 2015. PMID: 26384303 Free PMC article.
Main changes in European Clinical Trials Regulation (No 536/2014).
Tenti E, Simonetti G, Bochicchio MT, Martinelli G. Tenti E, et al. Among authors: bochicchio mt. Contemp Clin Trials Commun. 2018 May 17;11:99-101. doi: 10.1016/j.conctc.2018.05.014. eCollection 2018 Sep. Contemp Clin Trials Commun. 2018. PMID: 30003173 Free PMC article.
Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia.
Bruno S, Bochicchio MT, Franchini E, Padella A, Marconi G, Ghelli Luserna di Rorà A, Venturi C, Raffini M, Prisinzano G, Ferrari A, Bandini L, Robustelli V, Pazzaglia M, Fontana MC, Sartor C, Abbenante MC, Papayannidis C, Soverini S, Ottaviani E, Simonetti G, Martinelli G. Bruno S, et al. Among authors: bochicchio mt. J Oncol. 2019 Oct 30;2019:5985923. doi: 10.1155/2019/5985923. eCollection 2019. J Oncol. 2019. PMID: 31827512 Free PMC article.
MEC (mitoxantrone, etoposide, and cytarabine) induces complete remission and is an effective bridge to transplant in acute myeloid leukemia.
Marconi G, Talami A, Abbenante MC, Sartor C, Parisi S, Nanni J, Bertamini L, Ragaini S, Olivi M, de Polo S, Cristiano G, Fontana MC, Bochicchio MT, Ottaviani E, Arpinati M, Sessa M, Baldazzi C, Caso L, Testoni N, Baccarani M, Bonifazi F, Martinelli G, Paolini S, Cavo M, Papayannidis C, Curti A. Marconi G, et al. Among authors: bochicchio mt. Eur J Haematol. 2020 Jul;105(1):47-55. doi: 10.1111/ejh.13406. Epub 2020 Apr 7. Eur J Haematol. 2020. PMID: 32145118
Kevetrin induces apoptosis in TP53 wild‑type and mutant acute myeloid leukemia cells.
Napolitano R, De Matteis S, Carloni S, Bruno S, Abbati G, Capelli L, Ghetti M, Bochicchio MT, Liverani C, Mercatali L, Calistri D, Cuneo A, Menon K, Musuraca G, Martinelli G, Simonetti G. Napolitano R, et al. Among authors: bochicchio mt. Oncol Rep. 2020 Oct;44(4):1561-1573. doi: 10.3892/or.2020.7730. Epub 2020 Aug 11. Oncol Rep. 2020. PMID: 32945487 Free PMC article.
Safety profile and impact on survival of tyrosine kinase inhibitors versus conventional therapy in relapse or refractory FLT3 positive acute myeloid leukemia patients.
Marconi G, De Polo S, Martinelli G, Nanni J, Bertamini L, Talami A, Olivi M, Ragaini S, Abbenante MC, Sartor C, Ottaviani E, Bochicchio MT, Parisi S, Fontana MC, Cristiano G, Raffini M, Baldazzi C, Testoni N, Bonifazi F, Paolini S, Curti A, Cavo M, Papayannidis C. Marconi G, et al. Among authors: bochicchio mt. Leuk Res. 2021 Feb;101:106497. doi: 10.1016/j.leukres.2020.106497. Epub 2020 Dec 25. Leuk Res. 2021. PMID: 33385697 Clinical Trial.
Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations.
Simonetti G, Mengucci C, Padella A, Fonzi E, Picone G, Delpino C, Nanni J, De Tommaso R, Franchini E, Papayannidis C, Marconi G, Pazzaglia M, Perricone M, Scarpi E, Fontana MC, Bruno S, Tebaldi M, Ferrari A, Bochicchio MT, Ghelli Luserna Di Rorà A, Ghetti M, Napolitano R, Astolfi A, Baldazzi C, Guadagnuolo V, Ottaviani E, Iacobucci I, Cavo M, Castellani G, Haferlach T, Remondini D, Capozzi F, Martinelli G. Simonetti G, et al. Among authors: bochicchio mt. Leukemia. 2021 Oct;35(10):2813-2826. doi: 10.1038/s41375-021-01318-x. Epub 2021 Jun 30. Leukemia. 2021. PMID: 34193978 Free PMC article.
Measurable Residual Disease and Clonal Evolution in Acute Myeloid Leukemia from Diagnosis to Post-Transplant Follow-Up: The Role of Next-Generation Sequencing.
Sperotto A, Bochicchio MT, Simonetti G, Buccisano F, Peccatori J, Piemontese S, Calistri E, Ciotti G, Pierdomenico E, De Marchi R, Ciceri F, Gottardi M. Sperotto A, et al. Among authors: bochicchio mt. Biomedicines. 2023 Jan 26;11(2):359. doi: 10.3390/biomedicines11020359. Biomedicines. 2023. PMID: 36830896 Free PMC article. Review.
28 results