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Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy.
Redondo-Muñoz M, Rodriguez-Baena FJ, Aldaz P, Caballé-Mestres A, Moncho-Amor V, Otaegi-Ugartemendia M, Carrasco-Garcia E, Olias-Arjona A, Lasheras-Otero I, Santamaria E, Bocanegra A, Chocarro L, Grier A, Dzieciatkowska M M, Bigas C, Martin J, Urdiroz-Urricelqui U, Marzo F, Santamaria E, Kochan G, Escors D, Larrayoz IM, Heyn H, D'Alessandro A, Attolini CS, Matheu A, Wellbrock C, Benitah SA, Sanchez-Laorden B, Arozarena I. Redondo-Muñoz M, et al. Among authors: bocanegra a. Nat Metab. 2023 Sep;5(9):1544-1562. doi: 10.1038/s42255-023-00861-4. Epub 2023 Aug 10. Nat Metab. 2023. PMID: 37563469 Free PMC article.
PD-L1 Expression in Systemic Immune Cell Populations as a Potential Predictive Biomarker of Responses to PD-L1/PD-1 Blockade Therapy in Lung Cancer.
Bocanegra A, Fernandez-Hinojal G, Zuazo-Ibarra M, Arasanz H, Garcia-Granda MJ, Hernandez C, Ibañez M, Hernandez-Marin B, Martinez-Aguillo M, Lecumberri MJ, Fernandez de Lascoiti A, Teijeira L, Morilla I, Vera R, Escors D, Kochan G. Bocanegra A, et al. Int J Mol Sci. 2019 Apr 2;20(7):1631. doi: 10.3390/ijms20071631. Int J Mol Sci. 2019. PMID: 30986912 Free PMC article.
Functional systemic CD4 immunity is required for clinical responses to PD-L1/PD-1 blockade therapy.
Zuazo M, Arasanz H, Fernández-Hinojal G, García-Granda MJ, Gato M, Bocanegra A, Martínez M, Hernández B, Teijeira L, Morilla I, Lecumberri MJ, Fernández de Lascoiti A, Vera R, Kochan G, Escors D. Zuazo M, et al. Among authors: bocanegra a. EMBO Mol Med. 2019 Jul;11(7):e10293. doi: 10.15252/emmm.201910293. Epub 2019 Jun 6. EMBO Mol Med. 2019. PMID: 31273938 Free PMC article.
Early Detection of Hyperprogressive Disease in Non-Small Cell Lung Cancer by Monitoring of Systemic T Cell Dynamics.
Arasanz H, Zuazo M, Bocanegra A, Gato M, Martínez-Aguillo M, Morilla I, Fernández G, Hernández B, López P, Alberdi N, Hernández C, Chocarro L, Teijeira L, Vera R, Kochan G, Escors D. Arasanz H, et al. Among authors: bocanegra a. Cancers (Basel). 2020 Feb 4;12(2):344. doi: 10.3390/cancers12020344. Cancers (Basel). 2020. PMID: 32033028 Free PMC article.
Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition.
Arasanz H, Hernández C, Bocanegra A, Chocarro L, Zuazo M, Gato M, Ausin K, Santamaría E, Fernández-Irigoyen J, Fernandez G, Santamaria E, Rodríguez C, Blanco-Luquin I, Vera R, Escors D, Kochan G. Arasanz H, et al. Among authors: bocanegra a. Cancers (Basel). 2020 Aug 5;12(8):2181. doi: 10.3390/cancers12082181. Cancers (Basel). 2020. PMID: 32764385 Free PMC article.
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