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Chiral 2-phenyl-3-hydroxypropyl esters as PKC-alpha modulators: HPLC enantioseparation, NMR absolute configuration assignment, and molecular docking studies.
Linciano P, Nasti R, Listro R, Amadio M, Pascale A, Potenza D, Vasile F, Minneci M, Ann J, Lee J, Zhou X, Mitchell GA, Blumberg PM, Rossi D, Collina S. Linciano P, et al. Among authors: blumberg pm. Chirality. 2022 Mar;34(3):498-513. doi: 10.1002/chir.23406. Epub 2021 Dec 28. Chirality. 2022. PMID: 34962318
2-(Halogenated Phenyl) acetamides and propanamides as potent TRPV1 antagonists.
Kang JM, Kwon SO, Ann J, Lee S, Kim C, Do N, Jeong JJ, Blumberg PM, Ha H, Vu TNL, Yoon S, Choi S, Frank-Foltyn R, Lesch B, Bahrenberg G, Stockhausen H, Christoph T, Lee J. Kang JM, et al. Among authors: blumberg pm. Bioorg Med Chem Lett. 2021 Sep 15;48:128266. doi: 10.1016/j.bmcl.2021.128266. Epub 2021 Jul 14. Bioorg Med Chem Lett. 2021. PMID: 34273488
Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift.
Thorat SA, Lee Y, Jung A, Ann J, Ahn S, Baek J, Zuo D, Do N, Jeong JJ, Blumberg PM, Esch TE, Turcios NA, Pearce LV, Ha HJ, Yoo YD, Hong S, Choi S, Lee J. Thorat SA, et al. Among authors: blumberg pm. J Med Chem. 2021 Jan 14;64(1):370-384. doi: 10.1021/acs.jmedchem.0c00982. Epub 2021 Jan 1. J Med Chem. 2021. PMID: 33385210
Discovery of indane propanamides as potent and selective TRPV1 antagonists.
Ahn S, Kim YS, Kim MS, Ann J, Ha H, Yoo YD, Kim YH, Blumberg PM, Frank-Foltyn R, Bahrenberg G, Stockhausen H, Christoph T, Lee J. Ahn S, et al. Among authors: blumberg pm. Bioorg Med Chem Lett. 2020 Feb 1;30(3):126838. doi: 10.1016/j.bmcl.2019.126838. Epub 2019 Dec 3. Bioorg Med Chem Lett. 2020. PMID: 31864799
443 results