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Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics.
Blum G, Gazit A, Levitzki A. Blum G, et al. J Biol Chem. 2003 Oct 17;278(42):40442-54. doi: 10.1074/jbc.M305490200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869569 Free article.
AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, G., Gazit, A., and Levitzki, A. (2000) Biochemistry 39, 15705-15712). ...
AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, …
Synthesis of a novel macrocyclic library: discovery of an IGF-1R inhibitor.
Qvit N, Reuveni H, Gazal S, Zundelevich A, Blum G, Niv MY, Feldstein A, Meushar S, Shalev DE, Friedler A, Gilon C. Qvit N, et al. Among authors: blum g. J Comb Chem. 2008 Mar-Apr;10(2):256-66. doi: 10.1021/cc700113c. Epub 2008 Feb 14. J Comb Chem. 2008. PMID: 18271560
Improved Cathepsin Probes for Sensitive Molecular Imaging.
Yitzhak Y, Gaikwad H, Weiss-Sadan T, Merquiol E, Turk B, Blum G. Yitzhak Y, et al. Among authors: blum g. Molecules. 2022 Jan 27;27(3):842. doi: 10.3390/molecules27030842. Molecules. 2022. PMID: 35164107 Free PMC article.
Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3.
Alishekevitz D, Gingis-Velitski S, Kaidar-Person O, Gutter-Kapon L, Scherer SD, Raviv Z, Merquiol E, Ben-Nun Y, Miller V, Rachman-Tzemah C, Timaner M, Mumblat Y, Ilan N, Loven D, Hershkovitz D, Satchi-Fainaro R, Blum G, Sleeman JP, Vlodavsky I, Shaked Y. Alishekevitz D, et al. Among authors: blum g. Cell Rep. 2016 Oct 25;17(5):1344-1356. doi: 10.1016/j.celrep.2016.09.083. Cell Rep. 2016. PMID: 27783948 Free PMC article.
181 results