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Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors.
Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Pinto A, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA, Lopes LV. Temido-Ferreira M, et al. Among authors: blum d. Mol Psychiatry. 2020 Aug;25(8):1876-1900. doi: 10.1038/s41380-018-0110-9. Epub 2018 Jun 27. Mol Psychiatry. 2020. PMID: 29950682 Free PMC article.
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL. Chatterjee S, et al. Among authors: blum d. EMBO Mol Med. 2018 Nov;10(11):e8587. doi: 10.15252/emmm.201708587. EMBO Mol Med. 2018. PMID: 30275019 Free PMC article.
New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease.
Sergeant N, Vingtdeux V, Eddarkaoui S, Gay M, Evrard C, Le Fur N, Laurent C, Caillierez R, Obriot H, Larchanché PE, Farce A, Coevoet M, Carato P, Kouach M, Descat A, Dallemagne P, Buée-Scherrer V, Blum D, Hamdane M, Buée L, Melnyk P. Sergeant N, et al. Among authors: blum d. Neurobiol Dis. 2019 Sep;129:217-233. doi: 10.1016/j.nbd.2019.03.028. Epub 2019 Mar 27. Neurobiol Dis. 2019. PMID: 30928644
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D, Delarasse C; NeuroCEB Brain Bank. Carvalho K, et al. Among authors: blum d. Prog Neurobiol. 2021 Nov;206:102139. doi: 10.1016/j.pneurobio.2021.102139. Epub 2021 Aug 12. Prog Neurobiol. 2021. PMID: 34391810 Free article.
Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.
Belarbi K, Burnouf S, Fernandez-Gomez FJ, Laurent C, Lestavel S, Figeac M, Sultan A, Troquier L, Leboucher A, Caillierez R, Grosjean ME, Demeyer D, Obriot H, Brion I, Barbot B, Galas MC, Staels B, Humez S, Sergeant N, Schraen-Maschke S, Muhr-Tailleux A, Hamdane M, Buée L, Blum D. Belarbi K, et al. Among authors: blum d. Neurobiol Dis. 2011 Aug;43(2):486-94. doi: 10.1016/j.nbd.2011.04.022. Epub 2011 May 4. Neurobiol Dis. 2011. PMID: 21569847
587 results