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Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Sawitzki B, et al. Among authors: bluestone ja. Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. Lancet. 2020. PMID: 32446407 Free PMC article.
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability.
Huynh A, DuPage M, Priyadharshini B, Sage PT, Quiros J, Borges CM, Townamchai N, Gerriets VA, Rathmell JC, Sharpe AH, Bluestone JA, Turka LA. Huynh A, et al. Among authors: bluestone ja. Nat Immunol. 2015 Feb;16(2):188-96. doi: 10.1038/ni.3077. Epub 2015 Jan 5. Nat Immunol. 2015. PMID: 25559257 Free PMC article.
Targeting Treg signaling for the treatment of autoimmune diseases.
Spence A, Klementowicz JE, Bluestone JA, Tang Q. Spence A, et al. Among authors: bluestone ja. Curr Opin Immunol. 2015 Dec;37:11-20. doi: 10.1016/j.coi.2015.09.002. Epub 2015 Sep 29. Curr Opin Immunol. 2015. PMID: 26432763 Free PMC article. Review.
Type 1 diabetes immunotherapy using polyclonal regulatory T cells.
Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, Rieck M, Sayre PH, Tang Q. Bluestone JA, et al. Sci Transl Med. 2015 Nov 25;7(315):315ra189. doi: 10.1126/scitranslmed.aad4134. Sci Transl Med. 2015. PMID: 26606968 Free PMC article. Clinical Trial.
535 results