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Control of insulin secretion by GLP-1.
Jones B, Bloom SR, Buenaventura T, Tomas A, Rutter GA. Jones B, et al. Among authors: bloom sr. Peptides. 2018 Feb;100:75-84. doi: 10.1016/j.peptides.2017.12.013. Peptides. 2018. PMID: 29412835 Free article. Review.
The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists.
Fang Z, Chen S, Pickford P, Broichhagen J, Hodson DJ, Corrêa IR Jr, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: bloom sr. ACS Pharmacol Transl Sci. 2020 Mar 17;3(2):345-360. doi: 10.1021/acsptsci.0c00022. eCollection 2020 Apr 10. ACS Pharmacol Transl Sci. 2020. PMID: 32296773 Free PMC article.
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, Shchepinova MM, Corrêa IR Jr, Hodson DJ, Broichhagen J, Tate EW, Reimann F, Salem V, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: bloom sr. Int J Mol Sci. 2020 Nov 9;21(21):8404. doi: 10.3390/ijms21218404. Int J Mol Sci. 2020. PMID: 33182425 Free PMC article.
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
Jones B, McGlone ER, Fang Z, Pickford P, Corrêa IR Jr, Oishi A, Jockers R, Inoue A, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Tomas A, Bloom SR. Jones B, et al. Among authors: bloom sr. J Biol Chem. 2021 Jan-Jun;296:100133. doi: 10.1074/jbc.RA120.016334. Epub 2020 Dec 4. J Biol Chem. 2021. PMID: 33268378 Free PMC article.
Acylation of the Incretin Peptide Exendin-4 Directly Impacts Glucagon-Like Peptide-1 Receptor Signaling and Trafficking.
Lucey M, Ashik T, Marzook A, Wang Y, Goulding J, Oishi A, Broichhagen J, Hodson DJ, Minnion J, Elani Y, Jockers R, Briddon SJ, Bloom SR, Tomas A, Jones B. Lucey M, et al. Among authors: bloom sr. Mol Pharmacol. 2021 Oct;100(4):319-334. doi: 10.1124/molpharm.121.000270. Epub 2021 Jul 27. Mol Pharmacol. 2021. PMID: 34315812 Free PMC article.
1,725 results