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The Escherichia coli clamp loader can actively pry open the β-sliding clamp.
Paschall CO, Thompson JA, Marzahn MR, Chiraniya A, Hayner JN, O'Donnell M, Robbins AH, McKenna R, Bloom LB. Paschall CO, et al. Among authors: bloom lb. J Biol Chem. 2011 Dec 9;286(49):42704-42714. doi: 10.1074/jbc.M111.268169. Epub 2011 Oct 4. J Biol Chem. 2011. PMID: 21971175 Free PMC article.
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp.
Ason B, Handayani R, Williams CR, Bertram JG, Hingorani MM, O'Donnell M, Goodman MF, Bloom LB. Ason B, et al. Among authors: bloom lb. J Biol Chem. 2003 Mar 21;278(12):10033-40. doi: 10.1074/jbc.M211741200. Epub 2003 Jan 8. J Biol Chem. 2003. PMID: 12519754 Free article.
65 results