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A tight interplay between platelet activation and mitochondrial DNA release promotes platelet storage lesion in platelet concentrates.
Haeri K, Samiee S, Beigi P, Hajati S, Deyhim MR. Haeri K, et al. Vox Sang. 2024 May;119(5):439-446. doi: 10.1111/vox.13600. Epub 2024 Feb 22. Vox Sang. 2024. PMID: 38385820
Moreover, elevated free mitochondrial DNA (mtDNA) levels in PCs are associated with a higher risk of adverse transfusion reactions. Therefore, we aimed to evaluate the correlation between platelet activation markers and mtDNA release during PC storage. ...CONCLUSION: The i …
Moreover, elevated free mitochondrial DNA (mtDNA) levels in PCs are associated with a higher risk of adverse transfusion reactions. T …
Comparison mitochondrial DNA DAMPs changes in platelet prepared by apheresis and PRP.
Chegini A, Vakili L, Samiee S, Shaiegan M. Chegini A, et al. Ther Apher Dial. 2023 Jun;27(3):517-522. doi: 10.1111/1744-9987.13950. Epub 2022 Nov 23. Ther Apher Dial. 2023. PMID: 36385739
INTRODUCTION: Mt DNA (DAMPs) plays a key modulatory role in immune cells and may also mediate a variety of adverse transfusion reactions. MATERIAL AND METHOD: The cross-sectional study was performed on 22 (PRP) and 14 (SDP) between February 2019 and 2020. mtDNA DAMPs by qu …
INTRODUCTION: Mt DNA (DAMPs) plays a key modulatory role in immune cells and may also mediate a variety of adverse transfusion reacti …
Mannose binding lectin-associated serine protease 2 (MASP2) gene polymorphism and susceptibility to human T-lymphotropic virus type 1 (HTLV-1) infection in blood donors from Mashhad, Iran.
Aghamohammadi A, Rafatpanah H, Maghsoodlu M, Tohidi N, Mollahosseini F, Shahabi M. Aghamohammadi A, et al. Microbiol Immunol. 2022 Oct;66(10):460-464. doi: 10.1111/1348-0421.13022. Epub 2022 Aug 28. Microbiol Immunol. 2022. PMID: 35924689 Free article.
We aimed to investigate the role of genetic polymorphisms in the MASP2 gene and susceptibility to HTLV-1 infection. A total of 172 HTLV-1 infected individuals and 170 healthy blood donors were analyzed in this case-control study. Nine single nucleotide polymorphisms (SNPs) …
We aimed to investigate the role of genetic polymorphisms in the MASP2 gene and susceptibility to HTLV-1 infection. A total of 172 HTLV-1 in …
The effect of platelet apheresis collection on some immunological factors in donors using two different apheresis devices.
Chegini A, Fani P, Samiee S, Shaiegan M, Hajati E, Maghari A. Chegini A, et al. Ther Apher Dial. 2022 Oct;26(5):1040-1046. doi: 10.1111/1744-9987.13771. Epub 2021 Dec 16. Ther Apher Dial. 2022. PMID: 34859594
MATERIAL AND METHODS: The cross-sectional study was performed from January 2017 to September 2018. Fifty six male blood donors were randomly divided into two groups. CD4, CD8, and CD25 markers by flow cytometry, and TGFBeta by real-time polymerase chain reaction (RT-PCR) m …
MATERIAL AND METHODS: The cross-sectional study was performed from January 2017 to September 2018. Fifty six male blood donors were r …