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Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial.
Janssens SP, Bogaert J, Zalewski J, Toth A, Adriaenssens T, Belmans A, Bennett J, Claus P, Desmet W, Dubois C, Goetschalckx K, Sinnaeve P, Vandenberghe K, Vermeersch P, Lux A, Szelid Z, Durak M, Lech P, Zmudka K, Pokreisz P, Vranckx P, Merkely B, Bloch KD, Van de Werf F; NOMI investigators. Janssens SP, et al. Among authors: bloch kd. Eur Heart J. 2018 Aug 1;39(29):2717-2725. doi: 10.1093/eurheartj/ehy232. Eur Heart J. 2018. PMID: 29800130 Clinical Trial.
Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.
Liu X, Huang Y, Pokreisz P, Vermeersch P, Marsboom G, Swinnen M, Verbeken E, Santos J, Pellens M, Gillijns H, Van de Werf F, Bloch KD, Janssens S. Liu X, et al. Among authors: bloch kd. J Am Coll Cardiol. 2007 Aug 21;50(8):808-17. doi: 10.1016/j.jacc.2007.04.069. Epub 2007 Aug 6. J Am Coll Cardiol. 2007. PMID: 17707188 Free article.
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Janssens S, Pokreisz P, Schoonjans L, Pellens M, Vermeersch P, Tjwa M, Jans P, Scherrer-Crosbie M, Picard MH, Szelid Z, Gillijns H, Van de Werf F, Collen D, Bloch KD. Janssens S, et al. Among authors: bloch kd. Circ Res. 2004 May 14;94(9):1256-62. doi: 10.1161/01.RES.0000126497.38281.23. Epub 2004 Mar 25. Circ Res. 2004. PMID: 15044322 Free article.
Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.
Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP. Pokreisz P, et al. Among authors: bloch kd. Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12. Circulation. 2009. PMID: 19139381 Free PMC article.
Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury.
Hataishi R, Rodrigues AC, Neilan TG, Morgan JG, Buys E, Shiva S, Tambouret R, Jassal DS, Raher MJ, Furutani E, Ichinose F, Gladwin MT, Rosenzweig A, Zapol WM, Picard MH, Bloch KD, Scherrer-Crosbie M. Hataishi R, et al. Among authors: bloch kd. Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H379-84. doi: 10.1152/ajpheart.01172.2005. Epub 2006 Jan 27. Am J Physiol Heart Circ Physiol. 2006. PMID: 16443673 Free article.
Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin.
Neilan TG, Blake SL, Ichinose F, Raher MJ, Buys ES, Jassal DS, Furutani E, Perez-Sanz TM, Graveline A, Janssens SP, Picard MH, Scherrer-Crosbie M, Bloch KD. Neilan TG, et al. Among authors: bloch kd. Circulation. 2007 Jul 31;116(5):506-14. doi: 10.1161/CIRCULATIONAHA.106.652339. Epub 2007 Jul 16. Circulation. 2007. PMID: 17638931
Increased cardiac myocyte PDE5 levels in human and murine pressure overload hypertrophy contribute to adverse LV remodeling.
Vandenwijngaert S, Pokreisz P, Hermans H, Gillijns H, Pellens M, Bax NA, Coppiello G, Oosterlinck W, Balogh A, Papp Z, Bouten CV, Bartunek J, D'hooge J, Luttun A, Verbeken E, Herregods MC, Herijgers P, Bloch KD, Janssens S. Vandenwijngaert S, et al. Among authors: bloch kd. PLoS One. 2013;8(3):e58841. doi: 10.1371/journal.pone.0058841. Epub 2013 Mar 18. PLoS One. 2013. PMID: 23527037 Free PMC article.
243 results